BACKGROUND Refractory nonunions of the tibia or femur are physically and mentally devastating conditions for the patients, and the treatment is challenging for orthopedic surgeons. The goal of this study was to assess the feasibility and outcome of surgical treatment in recalcitrant nonunions of a lower extremity with bone graft enriched with autologous platelet gel (APG). METHODS Twelve pati...

PURPOSE To evaluate the clinical and radiological results of total knee arthroplasty (TKA) using the anterior-posterior glide (APG) low contact stress (LCS) mobile-bearing system. MATERIALS AND METHODS We evaluated 130 knees in 117 patients who had undergone TKA with APG LCS mobile-bearing system between September 2005 and July 2007 and could be followed over 5 years. The mean follow-up perio...

Physicochemical characteristics of pre-formulation concentrates of an emulsion system of LFAMEs/APG:organosilicone/water were determined. The surfactants used were octyl/decyl polyglucosides (short-chain APG; SAPG) and dodecyl/tetradecyl/hexadecyl polyglucosides (long-chain APG; LAPG). Alkyl chain length of the APG was found to dominate the different flow behaviours of emulsions. The SAPG-emuls...

The interaction of the dinucleotides d(ApG) and d(ApA) with [Pd(aa)Cl(2)], where aa = L- or D-histidine or the methyl ester of L-histidine, and with [Pt(Met)Cl(2)], where Met = L-methionine was studied by (1)H and (13)C NMR and CD measurements. In the case of the L-histidine and L-histidineOMe, the reaction with d(ApG) appeared to give the bifunctional adducts Pd(L-Histidine)N1(1)N7(2) and Pd(L...

On June 24, 2023, an Expert Council was held in St. Petersburg, during which leading experts the field of hematology discussed current achievements and answered a number unresolved issues targeted therapy paroxysmal nocturnal hemoglobinuria (APG) order to further improve treatment results Russia. During Council, following aspects APG were considered: • criteria for suboptimal response patients ...

Systems of computers and their application in the lives of modern human beings are vastly expanding. In any kind of computer application, failure in computer systems can lead to a range of financial and mortal losses. Indeed, the major origin of software failure can be located in designing or implementing software. With regard to these statistics, 30% of the software projects have been prospero...

BACKGROUND Dysconnectivity hypothesis of schizophrenia has been increasingly emphasized. Recent researches showed that this dysconnectivity might be related to occurrence of auditory hallucination (AH). However, there is still no consistent conclusion. This study aimed to explore intrinsic dysconnectivity pattern of whole-brain functional networks at voxel level in schizophrenic with AH. METH...

Autophagy is a degradative pathway by which cells sequester nonessential, bulk cytosol into double-membrane vesicles (autophagosomes) and deliver them to the vacuole for recycling. Using this strategy, eukaryotic cells survive periods of nutritional starvation. Under nutrient-rich conditions, autophagy machinery is required for the delivery of a resident vacuolar hydrolase, aminopeptidase I, by...

A multireference variant of coupled cluster theory is described that applies to systems that can qualitatively be described by deleting two electrons from a closed shell determinant, for example biradicals, single bond breaking processes, or valence excited states. The theory can be generalized to arbitrary open-shell systems and takes a form that is akin to equation-of-motion coupled cluster t...

The effect of adverse pressure gradient (APG) on near-wall turbulence is studied, with a particular attention to the production mechanism. A plane turbulent Couette flow considered for several values constant APG in lower wall region. direct numerical simulation (DNS) large computational domain shows that near continues exist even at sufficiently APGs. On increasing APG, cross-streamwise intens...