wide range of quinazolinone biological properties including: antibacterial, anticancer, and anti-inflammatory activities encouraged us to synthesis some fused quinazolinone derivatives. anthranilic acid was condensed with chloro acylchloride followed by dehydration to form the benzoxazinone intermediate; subsequent addition of an amine provided the fused quinazolinones. deoxyvasicinone which wa...

background: oxidation of lipids causes reduction of different properties of products that contains lipids. nowadays, there is a growing demand for the natural antioxidants due to the harmful effects of synthetic antioxidants such as bha, bht and tbhq. objective: in this study, extract of aerial parts of echinacea purpurea l. was used instead of synthetic antioxidants in cake then, antioxidant a...

objectives: the aim of the study was to achieve the health status of the iranian elderly migrants in australia. methods & materials: this study was done as a cross sectional survey carried out in 2005-2007 on 302 iranian immigrant aged 65 yrs and over who had lived in sydney metropolitan area for at least 6 months. results: the majority of the iranian elderly had a moderate level of anxiety and...

background and aims: human adenoviruses can cause a diversity of clinical diseases, but there is no antiviral therapy formally approved by adenovirus infections. thus, antiviral agents derived from medicinal plants which are effective against adenoviruses infections are urgently required. therefore, this research was aimed to evaluate in vitro antiadenovirus activity of pomegranate (punica gran...

objectives: the objective of this study was to analyze the fatty acid content, antioxidant, and antibacterial activities of hydro-methanolic extract of adonis wolgensis l. (a. wolgensis l.) growing wild in north of iran. materials and methods: oils of a. wolgensis l. was obtained by means of soxhlet apparatus from leaves and stems. methyl esters were derived from the oily mixtures by trans-este...

objectives: evaluation of therapeutic effects of carum copticum (c. copticum) has been the subject of several studies in recent years. thymol the major component of c. copticum is a widely known anti-microbial agent. in this study, the antibacterial and anti viral activities of essential oil of c. copticum fruit were determined. materials and methods: essential oil of c. copticum was analyzed b...

background: sport and exercise therapy can be used for low back pain's prevention. this research was aimed to evaluate the level of functional disability, pain intensity difference between the two groups of patients with chronic low back pain.   methods: this study was a cross-sectional-applied research conducted from december 2015 to march 2016 on the employed (n=50) and no employee peopl...

rosmarinus officinalis l., a medicinal herb from the labiates family, has been reported to be of potential benefit in the treatment and prevention of several diseases. in particular its phenolics have demonstrated protective effects on various types of cancer through several mechanisms. the present study aimed to determine the effects of rosemary phenolic extracts on human cell functions, with ...

?-amylase inhibitory activities of ethanol extracts from six selected iranian salvia species (s. hydrangea dc., s. hypoleuca benth., s. officinalis l., s. reuterana boiss., s. verticillata l. and s. virgata jacq.) were examined, using in vitro model. in addition, antioxidant capacities (dpph• radical scavenging) and total flavonoid cotents of the extracts were also determined. the results showe...

quinolone antibacterials are one of the most important classes of pharmacological agents known as potent inhibitors of bacterial dna gyrase and topoisomerase iv that efficiently inhibit dna replication and transcription by generating several double-stranded dna break. some quinolone derivatives demonstrated inhibitory potential against eukaryote topoismarase ii and substantial dose-dependent cy...