Plants adopt a series of strategies to tolerate solar UV-B radiation (with the side effects growth reduction), but positive have not been yet clarified. In this study, two cultivars with different leaf thickness for Chestnut rose (Rosa roxburghii Tratt), pioneering species ecological restoration in Karst region Southwest China, were employed investigate its responses ultraviolet-B (UV-B) exclus...

BACKGROUND In vitro bioassays are important in the evaluation of plants with possible hepatoprotective effects. The aims of this study were to evaluate the pretreatment of HepG2 cells with hepatoprotective agents against the damage induced by carbon tetrachloride (CCl4) and paracetamol (APAP). METHODS Antioxidative activity was measured using an assay to measure 2,2-diphenyl-1-picrylhydrazyl ...

Oxidative stress plays a pivotal role in the pathogenesis of atherosclerosis and can be effectively influenced by radical scavenging enzyme activity and expression. The vasoprotective effects of estrogens may be related to antioxidative properties. Therefore, effects of 17beta-estradiol on production of reactive oxygen species and radical scavenging enzymes were investigated. 17beta-estradiol d...

Protein-based drug delivery systems have gained popularity due to their intrinsic biocompatibility, straightforward surface modification, and potential for therapeutic activity. Among proteins, enzymes are particularly attractive because of specificity, efficient reaction rates, regeneration after substrate turnover, proven track record in the treatment diseases ranging from cancer inherited me...

Current research indicates that lipid peroxidation could have a role in aluminium toxicity. The aim of this study was to asses lipid peroxidation and antioxidative enzyme activity in erythrocytes of workers occupationally exposed to aluminium. We investigated a group of 59 workers (Al group) exposed to aluminium fumes (contamination factor F=8.07 to 13.47, national maximal allowed concentration...

Biomass growth, micronucleus induction, and antioxidative stress enzymes (superoxide dismutase, peroxidase, glutathione reductase, and catalase) were investigated simultaneously in the Vicia faba plant exposed to cadmium in solution. The biomass lowest-observed-effect concentration (LOEC) value was 2,000 microM Cd2+. In the shoots, enzymic activities increased without concentration-response rel...

The toxicity of chlortetracycline (CTC) on maize (Zea mays L.) growth and reactive oxygen species (ROS) generation was studied. The root and shoot lengths and fresh weights of maize seedlings were inhibited by CTC treatment (p < 0.05). Root length was more sensitive than other parameters with the EC10 value of 0.064 mg/L. The spin trapping technique followed by electron paramagnetic resonance (...

BACKGROUND The beneficial effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs), especially in dyslipidemic subjects with a high risk of cardiovascular disease, are widely described in the literature. A lot of effects of n-3 PUFAs and their oxidized metabolites are triggered by regulating the expression of genes. Currently, it is uncertain if the administration of n-3 PUFAs results in diff...

Seasonal changes in the total phenolic content, flavonoid content, specific activity of the enzyme polyphenol oxidase (PPO) and that of the antioxidative enzymes-catalase (CAT) and peroxidases (POX) were analyzed in three leafy liverworts, namely Solenostoma crenulata, Chiloscyphus gollani and Fossombronia himalayensis. In the rainy season (July–September), the plants were in their young juveni...

(+)-Catechin possesses a broad range of pharmacological properties, including antioxidative effect. However, little is reported on the mechanism by which (+)-catechin protects microglia cells from DNA damage by oxidative stress. In this study, TUNEL assay and DNA electrophorysis indicated that (+)-catechin markedly blocked DNA fragmentation and apoptosis of microglia cells by tBHP exposure. A p...