The antinociceptive and anti-inflammatory properties of Corchorus capsularis leaves chloroform extract were investigated in experimental animal models. The antinociceptive activity was measured using the writhing, hot plate and formalin tests, while the anti-inflammatory activity was measured using the carrageenan-induced paw edema test. The extract, obtained after 72 h soaking of the air-dried...

OBJECTIVE Vanillosmopsis arborea Baker (Asteraceae) has high economic value from Chapada to Araripe and its bark essential oil is a potential source of alpha-bisabolol. The present study aimed to elucidate the antinociceptive and antipruritic properties of the essential oil of V. arborea Baker (EOVA) in mice. MATERIALS AND METHODS The antinociceptive activity was assessed using the capsaicin,...

This study examined the antinociceptive and antiinflammatory activities of the stem bark of the traditional medicinal plant, Hildegardia poulifolia (Sterculiaceae), an endangered species. Methanolic bark extract of this species was investigated for the antinociceptive effect by using acetic acid-induced writhing and hot plate methods in albino mice and antiinflammatory activity by carrageenan, ...

Tricyclic antidepressant drugs induce antinociceptive effect and suggest that their analgesic action could be related to the monoaminergic activity of the drugs. The analgesic activity of amitriptyline was observed in mouse models of acute pain. Mice were divided into different groups and were given amitriptyline in different doses alone and in combination with morphine. Reaction time in Hot-Pl...

In traditional medicine, Bauhinia glauca subsp. hupehana has long been used as an analgesic agent in China. The aim of this study was to evaluate the antinociceptive activity of the ethanol extract of the aerial parts of B. glauca subsp. hupehana (BHE) in rats and its chemical fingerprint. The antinociceptive activity of BHE was assessed in mice using chemically and heat-induced pain models, su...

conclusions the experimental data verified that hebd leaves displayed remarkable antinociceptive activity. furthermore, the nonselective opioid receptor antagonist, naloxone blocked the antinociceptive effect of the extract in all tests, suggesting that hebd may act both at peripheral and central levels. results using writhing, tail-flick, and formalin tests, dramatic antinociceptive effects wer...