Urinary tract infections (UTIs) are one of the most common bacterial infections in humans. Current knowledge on antimicrobial susceptibility pattern is essential for appropriate therapy. Therefore the aim of the present study was to determine the distribution and antibiotic susceptibility pattern of bacterial strains, with special reference to ESBL, AmpC β-lactamase and MRSA production. A total...

To the Editor: Typhoid fever, caused by Salmonella enterica sero-var Typhi, is a serious form of enteric fever. In 2000, the worldwide number of typhoid cases was estimated to be >21,000,000, and there were >200,000 deaths from this disease (1). Ciprofl oxacin is the fi rst-line drug of choice for treatment of patients with typhoid fever, but there has been an increase in strains resistant to c...

Nontyphoidal Salmonella infections caused by antimicrobial-resistant (AMR) strains are of great public health concern. We compared the phenotypic and genotypic relationships among temporally and spatially related AMR Salmonella isolates (n=1058) representing several predominant serovars, including Salmonella Typhimurium, Salmonella Typhimurium var. 5-, Salmonella Derby, Salmonella Heidelberg, S...

The common practice in antibacterial drug development has been to rapidly make an attempt to find ever-more stable and broad-spectrum variants for a particular antibiotic, once a drug resistance for that antibiotic is detected. We are now facing bacterial resistance toward our clinically relevant antibiotics of such a magnitude that the conversation for antimicrobial drug development ought to i...

knowledge of antimicrobial resistance patterns in e. coli, the predominant pathogen associated with urinary tract infections (uti) is important as a guide in selecting empirical antimicrobial therapy. methods: to describe the antimicrobial susceptibility of e. coli associated with uti in a major university hospital in tehran (iran), seventy-six clinical isolates of e. coli were studied for susc...

background and objectives: shigellosis is an acute gastroenteritis that is one of the most common causes of morbidity and mortality in children with diarrhea in developing countries. the purpose of this study was to describe the distribution of shigella serogroups and serotypes and their antibacterial drug resistance profiles. materials and methods: fecal samples of all children suffering from ...

Haemophilus ducreyi resists the cytotoxic effects of human antimicrobial peptides (APs), including α-defensins, β-defensins, and the cathelicidin LL-37. Resistance to LL-37, mediated by the sensitive to antimicrobial peptide (Sap) transporter, is required for H. ducreyi virulence in humans. Cationic APs are attracted to the negatively charged bacterial cell surface. In other gram-negative bacte...

BACKGROUND For proper treatment of bacterial infections in mink, knowledge of the causative agents and their antimicrobial susceptibility patterns is crucial. The used antimicrobials are in general not registered for mink, i.e. most usage is "off-label". In this study, we report the patterns of antimicrobial resistance among pathogenic bacteria isolated from Danish mink during the period 2014-2...

background: the prevalence of antimicrobial resistance among enterobacteriaceae is increasing worldwide. identification of pathogens and their resistance to antimicrobials is mandatory for successful empiric antibiotic treatment. the aim of this study was to investigate the prevalence of antimicrobial resistance of enterobacteriaceae isolated from hospital-acquired and community-acquired infect...

background and objectives: neisseria gonorrhoeae is the second most sexually transmitted diseases agents in developing countries. antimicrobial resistance strains have created serious health concern. the aim of this study was to determine the frequency of endocervical gonococcal infection and antimicrobial susceptibility of n.gonorrhoeae in kashan, iran. materials and methods: in this study, 29...