OBJECTIVES To assess the incidence and significance of anticardiolipin antibodies after myocardial infarction and in unstable angina. DESIGN A prospective study of all patients under 60 admitted to the coronary care unit over a 12 month period with a diagnosis of acute myocardial infarction who were followed up for a further 12 months. Patients admitted with unstable angina were similarly ass...

We investigated the association of anticardiolipin antibodies (aCL) with epilepsy development and characteristics in children. This prospective case-control study included 40 epileptic children sex- age-matched controls. Epileptic had higher levels aCL compared to healthy controls (5.66 ± 5.41 versus 2.37 2.28; p value = 0.001). The novel finding elevated predicted response IVIg therapy (p 0.00...

background: severe preeclampsia is a quite well-known entity with high incidence of both maternal and fetal morbidity and mortality. although little is known about its etiology, inherited disorders of hemostasis and antiphospholipid syndrome have been postulated as common causes. the present study was conducted to evaluate the association of these two entities with preeclampsia in a group of ir...

Background: Antiphospholipid antibody syndrome (APS) can either occur as a primary syndrome or associated with other autoimmune diseases such as systemic lupus erythematosus (SLE). Anticardiolipin antibody (aCL) of IgG and/or IgM isotype in blood, measured by a standardized ELISA is the most acceptable laboratory criteria. APS IgG isotype, particularly IgG2 subclass is more strongly associated ...

Background : Abortion is termination of pregnancy by any means before the fetus is sufficiently developed to survive on its own. The growing recognition that in this group of patients there may be an immunologic basis aroused interest in research workers. The anticardiolipin antibodies (aCL) which are commonly associated with recurrent pregnancy loss are lgG and lgM. lgM antibody is the largest...