نتایج جستجو برای: anti tyrosinase

تعداد نتایج: 366184  

Journal: :jundishapur journal of natural pharmaceutical products 0
foroogh namjoyan department of pharmacognosy, ahvaz jundishapur university of medical sciences, ahvaz, ir iran alireza jahangiri department of medicinal chemistry, ahvaz jundishapur university of medical sciences, ahvaz, ir iran mohammad ebrahim azemi department of pharmacognosy, ahvaz jundishapur university of medical sciences, ahvaz, ir iran elaheh arkian medicinal plant research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; medicinal plant research center, ahvaz jundishapur university of medical sciences, ahvaz, iran. tel: +98-9132803410 hamideh mousavi medicinal plant research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran

conclusions all plants could inhibit mushroom tyrosinase, but more investigations on human tyrosinase and clinical studies are needed. results the hydroalcoholic extract of p. alkekengi showed the most tyrosinase inhibitory effect with ic50 of 0.09 mg/ml vs. 0.38, 0.38 and 2.82 mg/ml of b. persicum, a. rosea and m. vulgare, respectively. m. vulgare exhibited uncompetitive inhibition and other p...

2017
Zuly Elizabeth Jiménez Pérez Ramya Mathiyalagan Josua Markus Yeon-Ju Kim Hyun Mi Kang Ragavendran Abbai Kwang Hoon Seo Dandan Wang Veronika Soshnikova Deok Chun Yang

There has been a growing interest in the design of environmentally affable and biocompatible nanoparticles among scientists to find novel and safe biomaterials. Panax ginseng Meyer berries have unique phytochemical profile and exhibit beneficial pharmacological activities such as antihyperglycemic, antiobesity, antiaging, and antioxidant properties. A comprehensive study of the biologically act...

2013
Tzu-Rong Su Jen-Jie Lin Chi-Chu Tsai Tsu-Kei Huang Zih-Yan Yang Ming-O Wu Yu-Qing Zheng Ching-Chyuan Su Yu-Jen Wu

Gallic acid is one of the major flavonoids found in plants. It acts as an antioxidant, and seems to have anti-inflammatory, anti-viral, and anti-cancer properties. In this study, we investigated the effects of gallic acid on melanogenesis, including the activation of melanogenesis signaling pathways. Gallic acid significantly inhibited both melanin synthesis and tyrosinase activity in a dose- a...

Journal: :Open Access Macedonian Journal of Medical Sciences 2022

BACKGROUND: Ultraviolet B (UVB) radiation is the main factor causing aberrant melanin pigments leading to skin hyperpigmentation. Retinoic acid and hydroquinone are primary preference for whitening agents in preventing However, these treatments could induce slight-to-severe irritation cancer. Mangosteen peel possesses α-mangostin, constituent of xanthones mangosteen that has potency as an anti-...

Journal: :Journal of Experimental & Clinical Cancer Research : CR 2009
Fabio Di Domenico Cesira Foppoli Carla Blarzino Marzia Perluigi Francesca Paolini Salvatrice Morici Raffaella Coccia Chiara Cini Federico De Marco

BACKGROUND Melanin synthesis, the elective trait of melanocytes, is regulated by tyrosinase activity. In tyrosinase-positive amelanotic melanomas this rate limiting enzyme is inactive because of acidic endo-melanosomal pH. The E5 oncogene of the Human Papillomavirus Type 16 is a small transmembrane protein with a weak transforming activity and a role during the early steps of viral infections. ...

2014
Kikumi Ogihara Yuko Naya Yoshiharu Okamoto Keishi Hata

Canine melanoma is the most common oral malignant tumor reported in the field of veterinary medicine. We found that lupeol, a lupine triterpene, inhibited mouse melanoma cell growth in vitro and in vivo by inducing cell differentiation. In the present study, we examined the differentiation-inducing activities of lupeol on 4 canine melanoma cells in vitro and in vivo. The induction of canine mel...

Journal: :Bioelectrochemistry 2002
Gang Wang Jing-Juan Xu Li-Hua Ye Jun-Jie Zhu Hong-Yuan Chen

A novel tyrosinase biosensor has been developed for a subpicomolar detection of phenols, which is based on the immobilization of tyrosinase in a positively charged chitosan film on a glassy carbon electrode. It was found that chitosan cross-linked with (3-aminooryloxypropyl) dimethoxymethylsilane is beneficial for the immobilization of tyrosinase. The large microscopic surface area and porous m...

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