Background & Objective: The Physalis alkekengi is a herbaceous plant belonging to Solanaceae family. According to research, this plant can help inhibit cancer cell growth. Materials & Methods: In this study, the extract of Physalis alkekengi was used to suppress angiogenesis in Balb/c mice. First, the MC4L2 cells were injected in the mice breastbone and the tumor began to grow in this area, th...

CX3CL1 secreted in the tumor microenvironment serves as a chemoattractant playing critical role metastasis of CX3CR1 expressing cancer cells. can be expressed both and immune-inhibitory myeloid cells to facilitate their migration. We generated novel monoclonal antibody against mouse that binds blocks CX3CL1-CX3CR1 interaction. next explored immune evasion strategies implemented by axis find it ...