نتایج جستجو برای: anti rodent materials

تعداد نتایج: 812198  

Journal: :Frontiers in bioscience 2012
Raphaelle Romieu-Mourez Daniel L Coutu Jacques Galipeau

During the last decade, mesenchymal stromal cells (MSCs) have generated numbers of clinical trials to address inflammatory diseases such as GVHD, Crohn's disease and lupus. Animal models and therapeutic protocols in patients have demonstrated their anti-inflammatory and immunosuppressive properties towards adaptive immune cells. However, the basis of their immune suppression remains hotly debat...

Journal: :The Journal of Cell Biology 1969
Lennart Boquist

In the course of ultrastructural studies on the morphology of the pancreatic islets of various rodent species used in current diabetes research, intranuclear rod-shaped structures were observed in the $-cells of mice . Since there appeared to be no previous reports on the occurrence of such structures in endocrine pancreas of any species, it was thought worth while to pay some further attention...

2011
Leon French Powell Patrick Cheng Tan Paul Pavlidis

Recent research in C. elegans and the rodent has identified correlations between gene expression and connectivity. Here we extend this type of approach to examine complex patterns of gene expression in the rodent brain in the context of regional brain connectivity and differences in cellular populations. Using multiple large-scale data sets obtained from public sources, we identified two novel ...

Journal: :Environmental Health Perspectives 1992
A Morgan R J Talbot

The effects of inhaled alpha-emitting actinides on the alveolar macrophage (AM) population of the rodent lung are reviewed and, in particular, of the effects of 239PuO2 on murine AM. The effects discussed include changes the AM pool size, macrophage diameter, mobility, phagocytic competence, and enzyme content. Finally, similarities in the dose-response relationships for the induction of nuclea...

Journal: :Toxicologic pathology 2014
J Mark Cline Darlene Dixon Jan Ernerudh Marijke M Faas Claudia Göhner Jan-Dirk Häger Udo R Markert Christiane Pfarrer Judit Svensson-Arvelund Eberhard Buse

This short review is derived from the peer-reviewed literature and the experience and case materials of the authors. Brief illustrated summaries are presented on the gross and histologic normal anatomy of rodent and macaque placentas, including typical organ weights, with comments on differences from the human placenta. Common incidental findings, background lesions, and induced toxic lesions a...

2003
LENNART BOQUIST

In the course of ultrastructural studies on the morphology of the pancreatic islets of various rodent species used in current diabetes research, intranuclear rod-shaped structures were observed in the $-cells of mice . Since there appeared to be no previous reports on the occurrence of such structures in endocrine pancreas of any species, it was thought worth while to pay some further attention...

2015
Xiao Hu Jacques Moisan Kinga Majchrzak Chuck Lesch Yahong Wang Brian Sanchez Xikui Liu Rodney Morgan David Mertz Dick Bousley Chad van Huis Don Skalitzky Clarke Taylor Thomas Aicher Peter Toogood Weiping Zou Gary Glick Chrystal Paulos Laura Carter

Background Enhancing tumor-directed immune responses has emerged as an important therapeutic approach to many cancers. Th17/Tc17 cells can mediate robust anti-tumor responses in rodent models and are associated with improved prognosis in some human cancers. RORgt is the key transcription factor controlling the development and function of these cells by supporting the expression of pro-inflammat...

Journal: :Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2008
J-H Lee J-W Kim N-Y Ko S-H Mun D-K Kim J-D Kim H-S Kim K-R Lee Y-K Kim M Radinger E Her W-S Choi

BACKGROUND Novel approaches are being explored to develop new therapies for various allergic diseases. Complementary and alternative medicines are considered to be promising avenues for the development of such new therapies. OBJECTIVES To investigate the effect of many Korean plants on the IgE-mediated allergic response in mast cells and in vivo, and its mechanism of action. MATERIALS AND M...

Journal: :iranian journal of immunology 0
helmout modjtahedi division of oncology, postgraduate medical school, university of surrey, guildford, surrey gu2 7xh, united kingdom

despite the major advances in conventional forms of treatment (i.e. surgical techniques, radiotherapy and chemotherapy) and improved survival rates, cancer is still the second leading cause of death in developing countries. one major limitation of cytotoxic drugs and radiation in the treatment of cancer patients is their inability to discriminate between malignant and normal tissues. this in tu...

Journal: :Tropical life sciences research 2017
Nur Elfieyra Syazana Hamdan Yee Ling Ng Wei Bin Lee Cheng Siang Tan Faisal Ali Anwarali Khan Yee Ling Chong

Rodents belong to the order Rodentia, which consists of three families in Borneo (i.e., Muridae, Sciuridae and Hystricidae). These include rats, mice, squirrels, and porcupines. They are widespread throughout the world and considered pests that harm humans and livestock. Some rodent species are natural reservoirs of hantaviruses (Family: Bunyaviridae) that can cause zoonotic diseases in humans....

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