A 44 year old lady with primary hypothyroidism presented with massive pericardial effusion without cardiac tamponade. Pericardial tap was done twice and the effusion resolved as the hypothyroid state improved. She remained hypertensive despite the euthyroid state. She was discharged well with L-thyroxine and anti-hypertensive therapy.

UNLABELLED Hypertension is an established target for long-term stroke prevention but procedures for management of hypertension in acute stroke are less certain. Here, we analyze basic science data to examine the impact of hypertension on candidate stroke therapies and of anti-hypertensive treatments on stroke outcome. METHODS Data were pooled from 3,288 acute ischemic stroke experiments (47,8...

The hexane insoluble fraction of the Garcinia dulcis (GD) flower extract comprises mainly camboginol and morelloflavone which possess potent in vivo vitro antioxidant properties. This study aimed to evaluate effects 4-week oral administration GD on arterial blood pressure (ABP) excretory function kidney 2-kidneys-1-clip (2K1C) renovascular hypertensive rats (total=12) compared sham operated (SO...

Hypertension is a common chronic condition that affects approximately 78,000,000 adults within the United States [1]. Hypertensive crisis is defined as severe hypertension with a blood pressure of greater than 180/120 mmHg, and may be further classified as urgency or emergency [2,3]. Hypertensive urgency occurs in the setting of days to weeks and patients present most commonly with a headache. ...

Hypertension is a major public health problem, but measures to reduce blood pressure and thus cardiovascular risk are complicated by the high prevalence of treatment resistance, despite the availability of multiple drugs. Drug side-effects contribute considerably to suboptimal blood pressure control. Clinicians must often rely on empirical methods to match patients with effective drug treatment...

Epidemiological evidence suggests that treatment with f l-blockers and diuretics increase the risk to develop diabetes. Prospective, randomized studies of antihypertensive drugs have demonstrated differences between different classes of drugs regarding effects on insulin sensitivity. Thus treatment with ,-blockers or diuretics is associated with impairment in insulin sensitivity, whereas most m...

mirtazapine is a new antidepressant that can increase noradrenergic and serotonergic neurotransmission. it is also a postsynaptic antagonist of 5-ht2 and 5-ht3. in addition, it has only a weak affinity for 5-ht1 receptors and has very weak muscarinic anticholinergic and histamine (h1) antagonist properties. we report a case of hypertensive urgency that ensued after a patient took a single low d...