نتایج جستجو برای: animal experimentation

تعداد نتایج: 224027  

Journal: :The American psychologist 1995
M Domjan J E Purdy

The general psychology course provides a unique opportunity to present the science of psychology to a wide audience. Informing the general public about the importance of animal research in psychology is especially important given contemporary concerns about animal rights and animal welfare. A study of 8 leading introductory psychology textbooks indicated that with the exception of principles of...

2015
TOM L. BEAUCHAMP DAVID DeGRAZIA AYSHA AKHTAR

Nonhuman animal ("animal") experimentation is typically defended by arguments that it is reliable, that animals provide sufficiently good models of human biology and diseases to yield relevant information, and that, consequently, its use provides major human health benefits. I demonstrate that a growing body of scientific literature critically assessing the validity of animal experimentation ge...

2008
Michael Lyvers

Carruthers' case against animal consciousness employs deeply flawed reasoning and is contradicted by both empirical and introspective evidence. Although in principle we cannot objectively establish for certain that anyone -human or otherwise -is phenomenally conscious, results of animal research on consciousness-changing drugs are uninterpretable unless one assumes that non-human animals have d...

Journal: :Physiological genomics 2003
Klaas Kramer Lewis B Kinter

Radiotelemetry is the "state of the art" for monitoring physiological functions in awake and freely moving laboratory animals, while minimizing stress artifacts. For researchers, especially those in the fields of pharmacology and toxicology, the technique provides a valuable tool for defining the physiological and pathophysiological consequences derived from advances molecular, cellular, and ti...

2014
Gordon P Otto Ralf A Claus

We agree with Bara and Joffe that there is a need for improvement of reporting quality in animal research (AR) [1]. Presenting details on both methods used and potential cofounders during AR is not only important to reproduce results, and to ensure animal welfare (AW) and public support, it is a duty when animals are compromised, stressed or sacrificed to understand diseases or to identify trea...

Journal: :Methods in molecular biology 2017
Jon D Laman Susanne M Kooistra Björn E Clausen

In light of an enhanced awareness of ethical questions and ever increasing costs when working with animals in biomedical research, there is a dedicated and sometimes fierce debate concerning the (lack of) reproducibility of animal models and their relevance for human inflammatory diseases. Despite evident advancements in searching for alternatives, that is, replacing, reducing, and refining ani...

Journal: :Pain 2010
Jeffrey S Mogil Karen D Davis Stuart W Derbyshire

There exists currently a fair degree of introspection in the pain research community about the value of animal research. This review represents a defense of animal research in pain. We discuss the inherent advantage of animal models over human research as well as the crucial complementary roles animal studies play vis-à-vis human imaging and genetic studies. Finally, we discuss recent developme...

2011
Tobias Kalenscher Marijn van Wingerden

Despite the rich tradition in psychology and biology, animals as research subjects have never gained a similar acceptance in microeconomics research. With this article, we counter this trend of negligence and try to convey the message that animal models are an indispensible complement to the literature on human economic decision making. This perspective review departs from a description of the ...

Journal: :Drug discovery today. Technologies 2013
Bart Laurijssens Fabienne Aujard Anisur Rahman

Animal disease models are considered important in the development of drugs for Alzheimer's disease. This brief review will discuss possible reasons why their success in identifying efficacious treatments has been limited, and will provide some thoughts on the role of animal experimentation in drug development. Specifically, none of the current models of Alzheimer's disease have either construct...

Journal: :ILAR journal 2003
David E Granstrom

Challenges and published guidelines associated with appropriate care and use of farm animals in agricultural research conducted outside the laboratory are briefly reviewed. The Animal Welfare Act (Title 9 of the 2000 Code of Federal Regulations), which regulates the care and use of agricultural animals in biomedical research, does not include livestock and poultry used in agricultural research....

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