Objetivo: Analisar e abordar as causas alterações relacionadas à hiperalfalipoproteinemia, tendo como comparação os padrões gerais da população. Metodologia: Realizou-se uma Revisão de Literatura Integrativa, na qual utilizou palavras chaves especificadas nas bases dados Pubmed Science Direct: “hyperalphalipoprotenemia” OUR “hyperalphalipoprotein” “HDLc”. Resultados: Pode-se destacar mutações e...

Lipasin (also known as C19ORF80, RIFL, ANGPTL8 and betatrophin) is a newly discovered circulating factor that regulates lipid metabolism and promotes pancreatic β-cell proliferation. Whether circulating levels of lipasin in humans are altered in a) type 2 diabetes; b) obesity and c) the postprandial state, however, is unknown. The current study aimed to compare serum lipasin levels in those who...

Betatrophin/ANGPTL8 is a newly identified hormone produced in liver and adipose tissue that has been shown to be induced as a result of insulin resistance and regulates lipid metabolism. Little is known about betatrophin level in humans and its association with T2D and metabolic risk factors. Plasma level of betatrophin was measured by ELISA in 1603 subjects: 1047 non-diabetic and 556 T2D subje...