نتایج جستجو برای: anemia of prematurity

تعداد نتایج: 21172806  

2004
Awais Rashid Gerd Kortuem

Adaptation is one of the key characteristics of pervasive computing applications. However, implementing adaptation using conventional development techniques is challenging as adaptation requirements tend to affect multiple elements of a pervasive environment. In this paper, we present our experience with implementing adaptation using aspect-oriented programming (AOP). We argue that the use of A...

Journal: :Chemical research in toxicology 2014
Timothy E H Allen Jonathan M Goodman Steve Gutsell Paul J Russell

Consumer and environmental safety decisions are based on exposure and hazard data, interpreted using risk assessment approaches. The adverse outcome pathway (AOP) conceptual framework has been presented as a logical sequence of events or processes within biological systems which can be used to understand adverse effects and refine current risk assessment practices in ecotoxicology. This framewo...

2005
Pascal Durr Tom Staijen Lodewijk Bergmans Mehmet Aksit

The AOP community has successfully promoted and illustrated the power and elegance of aspect-oriented programming. One of the main problems of Aspect-oriented programming is, however, the aspect interference problem. When multiple aspects are superimposed on the same join point, undesired or incorrect behavior may emerge due to the side effects of behavior of the aspects at the join point. In t...

2015

A method for scale up of UV/AOP reactors is outlined that uses bench scale testing to determine the UV dose required per log destruction (DL) of a particular contaminant. This can then be used in CFD Modeling to size a full-scale UV reactor and to test the reactor in performance trials. Methods for calculating dose based on the path length distribution in a UV reactor are given.

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2015
Edward J Perkins Philipp Antczak Lyle Burgoon Francesco Falciani Natàlia Garcia-Reyero Steve Gutsell Geoff Hodges Aude Kienzler Dries Knapen Mary McBride Catherine Willett

Adverse outcome pathways (AOPs) offer a pathway-based toxicological framework to support hazard assessment and regulatory decision-making. However, little has been discussed about the scientific confidence needed, or how complete a pathway should be, before use in a specific regulatory application. Here we review four case studies to explore the degree of scientific confidence and extent of com...

2010
Hicham Benkhai Sandra Lemanski Harald Below Jens Uwe Heiden Elke Below Jürgen Lademann Manfred Bornewasser Theo Balz Christine Chudaske Axel Kramer

Although regular exercise is known to promote health, it is also well known that competetive sports can lead to an increase of free radical production, and thus to a drop in antioxidative potential. Thus, the present study examined the effect of competetive sports on the antioxidative potential (AOP). Using chemoluminescence, the AOP was measured in the spontaneous urine of leisure and semi-pro...

2001
Yvonne Coady

Operating system code is complex. But, while substantial complexity is inherent to this domain, some complexity is caused by modularity problems. The goal of the work proposed here is to explore aspectoriented programming as a means of making this kind of complexity unnecessary. Towards this end, we need to identify aspects of the system, use the proposed mechanisms of AOP to modularize them, a...

2006
Roberto E. Lopez-Herrejon

Features are increments in program functionality and are the building blocks of product lines. Typical implementation of features using Object Oriented techniques commonly crosscuts several classes and interfaces. There exist many techniques that implement crosscuts, of which Aspect Oriented ones distinguish themselves by their support of dynamic crosscuts expressed with advice. Despite being a...

Journal: :Neurotoxicology 2017
Anna Bal-Price Pamela J Lein Kimberly P Keil Sunjay Sethi Timothy Shafer Marta Barenys Ellen Fritsche Magdalini Sachana M E Bette Meek

The Adverse Outcome Pathway (AOP) concept has recently been proposed to support a paradigm shift in regulatory toxicology testing and risk assessment. This concept is similar to the Mode of Action (MOA), in that it describes a sequence of measurable key events triggered by a molecular initiating event in which a stressor interacts with a biological target. The resulting cascade of key events in...

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