Although female sexual dysfunction is a problem with low priority, it can have a profound impact on quality of life. In women, the cycle of sexual response begins in the brain, where a memory, an image, a scent, music, or a fantasy acts as a trigger to prompt sexual arousal. Thus, the brain is really the key and starting place for treatment of sexual dysfunction. Decreased libido, altered arous...

PCOS was first recognized as a medical disease or syndrome in the West in 1845 in France. Its most distinctive sign is the pathologic appearance of sclerocystic changes on the larger than average ovaries, which appeared to have a thick, shiny, white coating overlying many rows of cysts on the surface of the ovary. These ovarian changes give PCOS its name. In 1990 a National Institute of Health ...

The etiology of androgenic alopecia (AGA) involves several factors, including genetics, androgens, age and nutrition. Digit-length ratio of the index and ring finger (2D:4D) is an indicator of prenatal exposure to sex hormones. There is a paucity of studies that systemically review the possible positive predictive value of 2D:4D in the development of AGA. We performed a single-site, descriptive...

Most striated duct (SD) cells in the adult mouse parotid gland (PAG) have a few small secretory granules. These granules, however, are usually too small and sparse to be detected using light microscopy. Our serial studies have suggested that these PAG SD cells belong to a group of hormone-responsive granular duct cells, similar to the granular convoluted tubule (GCT) cells found in the submandi...

Clinical and experimental evidence support a role for gonadal steroids in modulating the expression and course of autoimmune diseases such as lupus. Whether or not inherited variation in sensitivity to circulating androgenic hormones could influence the manifestations of such disease is, however, unknown. We sought to determine whether differences in androgen sensitivity conferred by variation ...

Differentiation of skeletal muscle and the formation of the neuromuscular junction are regulated by steroid hormones. The effects of androgens on ion channel proteins central to neuromuscular signalling have been investigated in differentiating mouse muscle C2 cells and in C2 cells that stably overexpress the rat androgen receptor (AR) cDNA. Neither the expression nor function of ACh receptors ...

The "win at all costs" mentality fuels athletes to seek performance-enhancing substances, such as anabolic-androgenic steroids, to gain an advantage over their opponents. Nonathletes espouse this same attitude to "win" the battle of attractiveness. An enhanced understanding of anabolic-androgenic steroids and the motivations behind their abuse will arm pediatricians with the ability to engage t...

Anabolic androgenic steroids are being more popular between bodybuilders and people who using gym to enhance their physiques. However, according the increase of laws prohibiting sales these substances without physician prescription, route getting administration practices have become dangerous. include many synthetic derivatives testosterone its play a significant role in medical treatment. Thes...

The male Macrobrachium species (giant freshwater prawn) typically achieve better growth and a larger harvest size than females. Hence, it is clear that the monosex culture of all-male prawn populations would be inexpensively advantageous. This study aimed to determine whether androgenic gland (AG) ablation induces sex reversal giant dacqueti. AG was ablated through bilateral microsurgery (AG ab...