Transactional Memory (TM) simplifies parallel programming by transferring responsibility for concurrency management from the programmer to the system. Nevertheless, a number of challenges must be addressed for TM to be widely adopted. This dissertation presents work towards improving the practicality of TM across three dimensions. The first challenge addressed is that of integrating TM with pop...

Transmembrane (TM) proteins have crucial roles in various cellular processes. The location of post-translational modifications (PTMs) on TM proteins is associated with their functional roles in various cellular processes. Given the importance of PTMs in the functioning of TM proteins, this study developed topPTM (available online at http://topPTM.cse.yzu.edu.tw), a new dbPTM module that provide...

Loss of endothelial thrombomodulin (TM) function is associated with macrovascular, microvascular, and inflammatory diseases. Loss of TM function impairs the generation of the anticoagulant protease activated protein C (aPC), which conveys important neuroprotective effects. Yet, the physiological relevance and the mechanism through which the TM-aPC system maintains nerve function remain unknown....

In service-oriented systems a constellation of services cooperate, sharing potentially sensitive information and responsibilities. Cooperation is only possible if the different participants trust each other. As trust may depend on many different factors, in a flexible framework for Trust Management (TM) trust must be computed by combining different types of information. In this paper we describ...