Promoter methylation status of O-6-methylguanine-DNA methyltransferase (MGMT), a DNA repair enzyme, is a critical biomarker in glioblastoma (GBM), as treatment decisions and clinical trial inclusion rely on its accurate assessment. However, interpretation of results is complicated by poor interassay reproducibility as well as a weak correlation between methylation status and expression levels o...

high purity fluorapatite (fa) with rod-like and spherical-like morphology was synthesized via sol-gel method. chemical characterization of fa powders was done by xrd and ftir analyses. crystallite samples were calculated using scherer method. morphology of fa powders was investigated with tem and sem images. the results revealed that increasing the time of hydrolysis of phosphate sols significa...

Introduction: The mechanism of action and metabolism of clozapine, a complex drug used in psychopharmacology, is not completely understood. The effects of this compound in human body are related to some interactions with serotonin and dopamine neurotransmitter receptors. To further elucidate the mechanism of action and to support ongoing drug metabolism studies, [14C] clozapine with suita...

This note addresses 3 issues that seem to pervade much of economic thought about individual decisions among uncertain alternatives: (1) Restricting primitives to just orderings of first-order gambles and not admitting, e.g., compound acts or joint receipt of consequences and gambles. (2) Great resistance to experimental findings that strongly suggest that most current theories fail descriptivel...

Distillation columns with a high-purity product (down to 7 ppm) have been studied. A steady state model is developed using a commercial process simulator. The model is validated against industrial data. Based on the model, three major optimal operational changes are identified. These are, lowering the location of the feed & side draw streams, increasing the pressure at the top of the distillati...

HYSYS process modeling software was used to analyze the effect of reflux ratio and number of trays on the purity of ethylene in a vapor recompression distillation column and also in an ordinary distillation column. Analysis of data showed that with increased pressure a higher reflux ratio is needed to obtain a purity of 99.9% for both towers. In addition number of trays was varied to see its ef...

In this paper, we investigate po-purity using finitely presented S-posets, and give some equivalent conditions under which an S-poset is absolutely po-pure. We also introduce strongly finitely presented S-posets to characterize absolutely pure S-posets. Similar to the acts, every finitely presented cyclic S-posets is isomorphic to a factor S-poset of a pomonoid S by a finitely generated right con...

Today it is commonplace for historical Jesus scholars to emphasize Jesus’ Jewishness. at the same time most new Testament scholars deny that he cared about the Jewish purity system, which was a central aspect of early Judaism. This article examines how such a reconstruction of the historical Jesus would influence his Jewishness, arguing that it indeed would make such a Jesus figure ‘less Jewish...

We associate with every quantum channel T acting on a Hilbert space H a pair of Hermitian operators, referred to as “Hamiltonians,” over the symmetric subspace of H^2. The expectation values of these Hamiltonians over symmetric product states give either the purity or the pure-state fidelity of T. This allows us to analytically compute these measures for a wide class of channels, and to identif...