PURPOSE To review epidemiologic studies on the association between homocyst(e)ine level and risk for cardiovascular disease and the potential benefits of homocysteine-decreasing therapies. DATA SOURCES Computerized and manual searches of the literature on total homocysteine levels and cardiovascular disease. STUDY SELECTION Prospective studies and major retrospective epidemiologic studies e...

Lemna perpusilla 6746, grown photoautotrophically at a series of sulfate concentrations ranging from 0.32 to 1,000 mum, was labeled to radioisotopic equilibrium with (35)SO(4) (2-). Sulfur-containing compounds were isolated and purified from the colonies. Radioactivity in each compound was a measure of the amount of that compound present in the tissue. The following compounds were identified an...

Background. Plasma levels of homocyst(e)ine are elevated in certain patients with occlusive arterial diseases. We extended these findings to asymptomatic adults. Methods and Results. We determined plasma homocyst(e)ine levels in 287 pairs of asymptomatic adults. Cases and controls were defined on the basis of intimal-medial thickness of the carotid wall as measured by B-mode ultrasound. Study s...

BACKGROUND AND PURPOSE Hyperhomocyst(e)inemia is emerging as a possible risk factor for stroke, possibly because of accelerated atherosclerosis. There are no previous publications evaluating homocyst(e)ine in young Asian ischemic stroke patients. We conducted a case-control study examining homocyst(e)ine, vitamin B12, and folate levels in young, first-ever Asian ischemic stroke patients. METH...

The responses of sympathetic nerve activity to transient stress can be exaggerated in salt-sensitive (SS), hypertensive subjects. Cardiac and renal interstitial norepinephrine (iNE) levels during and after transient hypercapnia were investigated in conscious SS rats. Dahl SS and salt-resistant (SR) 6-wk-old rats were fed a high-salt diet, and at 12 wk iNE levels in the heart and kidney were det...

a case of massive actinomyco tic empyema, the fi rst report in iran, in a girl of 20 yea rs o ld is presented with complete cu re after treatment by d rainage, penici llin and te tra cycl ine. the pathogenesis of actinornycetes and of o ther saprophytes is d iscu ssed. altho ugh the incidence of actinomycosis has decreased in the a ntibiotic era, the possib ility of the infection should be kept...