We are sympathetic with Bentley et al.'s attempt to encompass the wisdom of crowds in a generative model, but posit that a successful attempt at using big data will include more sensitive measurements, more varied sources of information, and will also build from the indirect information available through technology, from ancillary technical features to data from brain-computer interfaces.

A method of constrained parameter estimation is proposed for a class of computer vision problems. In a typical application, the parameters will describe a relationship between image feature locations, expressed as an equation linking the parameters and the image data, and will satisfy an ancillary constraint not involving the image data. A salient feature of the method is that it handles the an...

Fine needle cytology (FNC) is represents a valid tool in the diagnosis of lymphadenopathies. When rapid on site evaluation (ROSE) is performed the method overcomes the problems related to the adequacy and allows to store residual material for ancillary techniques future. Cytological data, obtained by FNC may be supported and integrated by ancillary techniques namely molecular biology. The detec...