Single Molecule Localization Microscopy techniques like PhotoActivated Localization Microscopy, with their sub-diffraction limit spatial resolution, have been popularly used to characterize the spatial organization of membrane proteins, by means of quantitative cluster analysis. However, such quantitative studies remain challenged by the techniques' inherent sources of errors such as a limited ...

Steps of an information networks’ creating through the formalization of one of their most important input parameters are proposed in the article. Stages of collecting information about users, the formalization of the data and analytical methods are described. The information networks’ user model is used to improve the efficiency and reliability of information networks’ modeling. In the proposed...

OBJECTIVES The aim of this paper is to identify the factors that determine the environmental domain of quality of life in economically active adults living in the industrial agglomeration in Poland. MATERIALS AND METHODS During the cross-sectional epidemiological study conducted among the economically active population aged 45-60, we used a short version of the WHOQOL-BREF questionnaire. Resp...

Contamination of pharmaceuticals with microorganisms may lead to deleterious effects on the therapeutic properties of the drug, and may potentially cause injuries to intended recipients. Cases of contaminated nonsterile products have been reported in increasing numbers, and often associated with the presence of objectionable microorganisms. Methods for detection of these organisms are described...

Abstract Reliability allocation is the key issue of reliability designing. CNC machine is a complex product. There are many influence factors of reliability allocation. A part of them cannot be accurately measured but be evaluated by the experts. Therefore it’s difficult for reliability allocation. In this paper, we consider a variety of criteria for conducting reliability allocation. A method ...

This paper presents a study of various researches which were come out in last few decades on hydro thermal scheduling problems. As we know that the Operation of mix both hydro and thermal plants is far more complex and is of much more importance in a modern power system. The aim of the hydrothermal scheduling problem is to optimize the electricity production and minimized the cost of power. Thi...

The need for multidisciplinary research to address today's complex health and environmental challenges has never been greater. The One Health (OH) approach to research ensures that human, animal, and environmental health questions are evaluated in an integrated and holistic manner to provide a more comprehensive understanding of the problem and potential solutions than would be possible with si...

Molecular diagnostics is a discipline that combines laboratory medicine with the knowledge and technology of molecular genetics. Its aim is to provide a sensitive alternative to protein-based current methodologies by developing DNA/RNA-based analytical methods for monitoring human pathologies. This is accomplished by the identification of the disease-causing mutations which may be both known or...

Developing internally valid, and perhaps generalizable, farmworker exposure studies is a complex process that involves many statistical and laboratory considerations. Statistics are an integral component of each study beginning with the design stage and continuing to the final data analysis and interpretation. Similarly, data quality plays a significant role in the overall value of the study. D...

Improved laboratory methods allow one to investigate the contribution of measured allelic variability at a locus physiologically involved in determining the expression of a quantitative trait. We present statistical methods that incorporate measured genotype information into the analysis of a quantitative phenotype that allows one simultaneously to detect and estimate the effects of a measured ...