Blood pressure (BP) is controlled by several mechanism, (i.e nitric oxide, (NO), neural mechanisms, renal-endocrine mechanisms. Many antihypertensive agents, such as diuretics, β-blockers, calcium-channel blockers, and blockers of the renninangiotensin system, such as angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers among others are used separately or in combination...