Practical relevance: Feline hypertension is a common disease in older cats that is frequently diagnosed in association with other diseases such as chronic kidney disease and hyperthyroidism (so-called secondary hypertension), although some cases of apparent primary hypertension are also reported. The clinical consequences of hypertension can be severe, related to 'target organ damage' (eye, hea...

BACKGROUND Role of renin-angiotensin aldosterone system (RAAS) in feline systemic hypertension is poorly understood. OBJECTIVES Examine plasma renin activity (PRA) and plasma aldosterone concentrations (PAC) in normotensive and hypertensive cats with variable renal function and in response to antihypertensive therapy. ANIMALS One hundred and ninety-six cats >9 years from first opinion pract...