ABERDEEN 29 s Aberdeen Research and Development Center AFETR s Air Force Eastern Test Range AFGWC see GWC ALOHA 35 i Aloha Network, University of Hawaii ALOHA-TIP 163 s Aloha Network, University of Hawaii AMEC see Belvoir AMES-67 16 NASA Ames Research Center AMES-ILLIAC see ILLIAC AMES-TIP 144 NASA Ames Research Center ARPA-TIP 156 Advanced Research Projects Agency BBN 1D 197 Bolt Beranek and N...

Stilbenes are secondary metabolites of great interest produced by many plant species due to their important bioactive properties. These phytochemicals have become increasing in the wine industry as a natural alternative sulphur dioxide, which has been associated with human health risks. However, there is still little toxicological information on stilbenes and results thus far contradictory. Con...

Background: Hospitals discharge considerable amounts of chemicals in their wastewaters that may be genotoxic or present serious health hazards. The genotoxic potential of wastewater in a Lebanese University Hospital was evaluated using the SOS Chromotest and the Ames fluctuation test. Different concentrations were tested to determine the recommended dilution for each sample to decrease its geno...

OBJECTIVES Emodin is a bioactive anthraquinone that has diverse biological effects. It is also known as a biosynthetic precursor of hypericin. The purpose of this study was to assess mechanisms of potential genotoxic and antioxidant effects of emodin. We also investigated the potential genotoxic effect of photoactivated emodin. METHODS Potential genotoxicity was determined by the alkaline com...

Anemopsis californica has been used empirically to treat infectious diseases. However, there are no antimutagenic evaluation reports on this plant. The present study evaluated the antioxidant activity in relation to the mutagenic and antimutagenic activity properties of leaf (LME) and stem (SME) methanolic extracts of A. californica collected in the central Mexican state of Querétaro. Antioxida...

Studies have shown that Casearia sylvestris compounds protect DNA from damage both in vitro and in vivo. Complementarily, the aim of the present study was to assess the chemopreventive effect of casearin B (CASB) against DNA damage using the Ames test, the comet assay and the DCFDA antioxidant assay. The genotoxicity was assessed by the comet assay in HepG2 cells. CASB was genotoxic at concentr...