Background Ameloblastoma is the most frequently encountered neoplasm arising from the odontogenic epithelium. Beclin-1 protein plays a critical role in autophagy as a tumor suppressor gene. Whereas, the Murine Double Minute 2 (MDM-2) is a cellular proto-oncogene capable, if amplified, of causing tumor-genesis. The expression & prognostic significance of both genes are largely unexplored, yet, i...

Ameloblastoma is a true neoplasm of odontogenic origin and benign in nature. But it has a high percentage of local recurrence with possible malignant development when treated inadequately. The treatment planning in ameloblastomas is still not clear. We describe a case report of unicystic plexiform ameloblastoma in a young girl who was treated with conservative surgical management (enucleation &...

Ameloblastoma, especially maxillary, is a rare benign neoplasm of odontogenic origin. Diagnosis of significant number of lesions is usually established postoperatively, because ameloblastoma, especially the unicystic form, mimics wide range of more frequent jaw lesions. From January 1993 to December 2005, three cases of the maxillary ameloblastoma were surgically treated at our Department. The ...

The aim of this study was to analyse the presence histological infiltrations neoplastic cells within bone, and compare distance these with radiografic limits ameloblastoma. For purpose, six integral surgical samples, identifiable radiographic tumor, sent Pathology Service Dental School Federal University Rio Grande do SuÌ, were processed. From resuÌts obtained, can be concluded úat, alúough ame...

AIM To investigate the expression of CD56 in dog odontogenesis in order to elucidate the expression found in ameloblastomas. MATERIALS AND METHODS Immunohistochemical analysis of CD56 expression of developing dog teeth in the bud, cap and bell stages including the remnants of the dental lamina. RESULTS Weak CD56 expression was observed in the dental epithelium during the bud stage with inte...

OBJECTIVE The aim of the study was to determine the apoptotic features and proliferation potential of odontogenic keratocysts compared with ameloblastomas and radicular cysts by analysing the role of bax, bcl-2, and Ki-67. MATERIAL AND METHOD The study material consisted of 20 odontogenic keratocysts, 20 radicular cysts, and 20 ameloblastomas. Immunohistochemically, bax, bcl-2 and Ki-67 were ...

OBJECTIVES A definite geographic variation has been observed in the frequency of odontogenic tumors and giant cell lesions of the jaws reported from different parts of the world. However, there are a few studies on these lesions, especially giant cell lesions, reported from India. Hence, this study was designed to provide a demographic data on the odontogenic tumors and giant cell lesions repor...

This review article aimed to introduce a category of jaw lesions associated with impacted tooth. General search engines and specialized databases such as Google Scholar, PubMed, PubMed Central, MedLine Plus, Science Direct, Scopus, and well-recognized textbooks were used to find relevant studies using keywords such as "jaw lesion", "jaw disease", "impacted tooth", and "unerupted tooth". More th...