BACKGROUND National Football League (NFL) players are exposed to multiple head collisions during their careers. Increasing awareness of the adverse long-term effects of repetitive head trauma has raised substantial concern among players, medical professionals, and the general public. OBJECTIVE To determine whether low perfusion in specific brain regions on neuroimaging can accurately separate...

Pathological inclusions containing aggregated, highly phosphorylated (at serine129) α-synuclein (αS pSer129) are characteristic of a group of neurodegenerative diseases termed synucleinopathies. Antibodies to the pSer129 epitope can be highly sensitive in detecting αS inclusions in human tissue and experimental models of synucleinopathies. However, the generation of extensively specific pSer129...

Purpose: To determine the prevalence of amblyopia and strabismus in the schoolchildren of the city of Bojnourd, Iran Methods: In 2010, randomized stratified cluster sampling was employed in a cross-sectional study on primary and junior high schoolchildren. All the examinations were performed in schools. All students received refraction, vision and subjective refraction tests. The cover test was...

The sharpened No-Free-Lunch-theorem (NFL-theorem) states that, regardless of the performance measure, the performance of all optimization algorithms averaged uniformly over any finite set F of functions is equal if and only if F is closed under permutation (c.u.p.). In this paper, we first summarize some consequences of this theorem, which have been proven recently: The number of subsets c.u.p....

BACKGROUND Bony augmentation of the anterior glenoid is used in athletes with recurrent shoulder instability and bone loss; however, the prevalence and impact of repair in elite American football athletes are unknown. PURPOSE To evaluate the prevalence and impact of glenoid augmentation in athletes invited to the National Football League (NFL) Scouting Combine from 2012 to 2015. STUDY DESIG...

BACKGROUND Blood biomarkers of neuronal damage could facilitate clinical management of and therapeutic development for Huntington's disease. We investigated whether neurofilament light protein NfL (also known as NF-L) in blood is a potential prognostic marker of neurodegeneration in patients with Huntington's disease. METHODS We did a retrospective analysis of healthy controls and carriers of...

A scaling consideration of the Kondo lattices is performed with account of singularities in the spin excitation spectral function. It is shown that a non-Fermi-liquid (NFL) behavior occurs naturally for complicated magnetic structures with several magnon branches. Another kind of a NFL-like state (with different crytical exponents) can occur for paramagnets with two-dimensional character of spi...

In this paper, a novel classifier based on nearest feature line is proposed, which is called as restricted nearest feature line with ellipse (RNFLE). NFL successfully improves the classification ability. However there are still some drawbacks in NFL that limit their further application in practice. To improve the miss-classification of nearest feature line when the prototypes in NFL are far awa...

The ”No Free Lunch” (NFL) theorems state that in average each algorithm has the same performance, when no a priori knowledge of single-objective cost function f is assumed. This paper extends the NFL theorems to the case of multi-objective optimization. Further it is shown that even in cases of a priori knowledge, when the performance measure is related to the set of extrema points sampled so f...

This paper proposes a new classification method termed Rectified Nearest Feature Line Segment (RNFLS). It overcomes the drawbacks of the original Nearest Feature Line (NFL) classifier and possesses a novel property that centralizes the probability density of the initial sample distribution, which significantly enhances the classification ability. Another remarkable merit is that RNFLS is applic...