In this paper we study hypercomplex manifolds in four dimensions. Rather than using an approach based on differential forms, we develop a dual approach using vector fields. The condition on these vector fields may then be interpreted as Lax equations, exhibiting the integrability properties of such manifolds. A number of different field equations for such hypercomplex manifolds are derived, one...

We present a method to extract polyhedral structures from a three-dimensional set of points, even if these structures are embedded in a perturbed background. The method is based on a family of affine diagrams which is an extension of the Voronoi diagram. These diagrams, namely anisotropic diagrams, are defined by using a parameterized distance whose unit ball is an ellipsoidal one. The paramete...

BACKGROUND Pin 1 is a peptidyl-prolyl isomerase inhibitor related to cyclophilin A and FK506 binding protein (FKBP). Juglone (5-hydroxy-1,4-naphthoquinone) is a natural inhibitor of Pin 1 with anti-inflammatory and antifibrotic properties. We evaluated the role of Pin 1 in renal fibrogenesis by evaluating the effects of juglone on epithelial to mesenchymal transition (EMT) and fibrogenesis in t...

Progressive immune dysfunction and AIDS develop in most cases of human immunodeficiency virus type 1 (HIV-1) infection but in only 25 to 30% of persons with HIV-2 infection. However, the natural history and immunologic responses of individuals with dual HIV-1 and HIV-2 infection are largely undefined. Based on our previous findings, we hypothesized that among patients with dual infection the co...

The surface of the airway epithelium represents a battleground in which the host intercepts signals from pathogens and activates epithelial defenses to combat infection. Wound repair is an essential function of the airway epithelium in response to injury in chronic airway diseases, and inhaled pathogens such as Pseudomonas bacteria are implicated in the pathobiology of several of these diseases...

As is the case in other tetrapod species, the chicken gonadotropins LH and FSH consist of a common alpha subunit and a hormone-specific beta subunit. Gonadotrophs containing LH were shown earlier to be distributed throughout both the caudal and cephalic lobes of the chicken anterior pituitary, but the cellular distribution of FSH in avian species is still uncertain. The purpose of this study wa...

We report a new and apparently unique human lymphoma cell line termed Deglis. The line was established from a polymorphic centroblastic lymphoma. The cell line and its source carry a dual B-cell and T-cell phenotype and Epstein-Barr virus (EBV) genomes. Simultaneous expression of B-cell (CD19+, CD20+, CD23+, CD37+) and T-cell (CD2+, CD3+/-, CD7+, CD43+) antigens, activation antigens (CD30+, CDw...

People with Parkinson’s disease (PD) have difficulty performing dual tasks or simultaneous movements, even if the same movements can be easily performed individually. This has particular significance clinically, as for example falling injuries may occur if care is not taken to perform tasks one at a time. We investigated whether this difficultyx results from impaired dopamine-modulated connecti...

In this paper, we have constructed a bottom-up holographic model for the color superconductivity (CSC) of Yang-Mills theory with including higher derivative corrections which allow us to study CSC phase number ${N}_{c}\ensuremath{\ge}2$. First, consider transition in context Einstein-Gauss-Bonnet (EGB) gravity. We analyze Cooper pair condensate deconfinement and confinement phases are dual plan...