BACKGROUND Cardiac allograft rejection and vasculopathy are the main factors limiting long-term survival after heart transplantation.In this pilot study we investigated whether non-invasive methods are beneficial to detect cardiac allograft rejection (Grade 03 R) and cardiac allograft vasculopathy. Thus we compared multi-slice computed tomography and magnetic resonance imaging with invasive met...

BACKGROUND Metapneumoviral respiratory infection is a community-acquired respiratory viral (CARV) infection. Lung transplantation recipients exposed to CARV are at risk for development of allograft rejection. The cellular and molecular pathways initiated by viral infection leading to allograft dysfunction are not completely understood. The aim of this study was to identify human metapneumoviral...

Glenoid and humeral head bone loss is the most common cause of failure after surgical shoulder instability stabilization. Large Hill-Sachs lesions involving >30% of the articular surface of the humeral head typically occur after neglected or locked shoulder dislocations. Such large lesions may require osteochondral allograft reconstruction or prosthetic replacement to regain shoulder stability ...

IL-17A is a proinflammatory cytokine that has received attention for its role in the pathogenesis of several autoimmune diseases. IL-17A has also been implicated in cardiac and renal allograft rejection. Accordingly, we hypothesized that depletion of IL-17A would enhance corneal allograft survival. Instead, our results demonstrate that blocking IL-17A in a mouse model of keratoplasty accelerate...

+*Jayabalan P; *Waters NP, *Cook CR; *Kuroki K; *Carson W; *Cook JL +*Comparative Orthopaedic Laboratory, University of Missouri, Columbia, MO [email protected] Introduction: Repair of chronic tears of the rotator cuff fail in 30-90% of cases. Current repair techniques do not re-establish normal bone-tendon (B-T) or tendon-muscle (T-M) junctions. Optimizing the strength and function at these ...

19 young children (less than 5 years old) have received 31 renal transplants from 4 live relatives and 27 cadaver donors. The 2-year allograft survival rate for the patients receiving their 1st allograft from the 4 live donors was 75 +/- 22% while for the patients receiving their 1st allograft from 15 cadaver donors was 26 +/- 11%. 10 children are currently surviving with functioning allographs...

  Background: Massive bone allograft is an option in cases of limb preservation and reconstruction after massive benign and malignant bone tumor resection. The purpose of this study was to analyze the outcome of these procedures at Imam Reza Hospital, Mashhad University of Medical Sciences. Methods: In this study, 113 cases have been presented. Eleven cases were excluded (patients has a traumat...

abstract  background: despite the long-standing association of macrophage migration inhibitory  factor (mif) with delayed-type hypersensitivity response, the potential role  of mif in chronic allograft nephropathy is unknown. the association between upregulation of mif expression, macrophage and t cell infiltration and the severity of  chronic allograft nephropathy suggests that mif may be an i...

chemical injuries of the cornea are ophthalmic emergencies. these injuries often result in significant ocular morbidity and generally strike young adults in the prime years of life. classification schemes enable the ophthalmologist to determine the severity of injury and the prognosis for the injured eye. immediate management consists of copious irrigation following exposure. effective manageme...

Vascular torsion in a renal allograft after placement in the retroperitoneum is rare and has only been reported twice in the literature. It is an extrinsically mediated process that occurs at the vascular pedicle resulting in graft compromise and potential loss. Rapid diagnosis and immediate surgical intervention may salvage allograft function. Herein, we present a unique case of a 42-year-old ...