نتایج جستجو برای: allogenic blood transfusion
تعداد نتایج: 694768 فیلتر نتایج به سال:
background and objective: patients with thalassemia major have an abnormality in hemoglobin synthesis and ineffective hematopoiesis and for this reason with respect to disease severity should receive one or more fresh blood unit every 15-30 days. since transfusion of blood products has been known as one of the routes of hiv infection, therefore, this study was conducted to evaluate the prevalen...
conclusions: hydroxyurea can be safely used in some transfusion-dependent β-thalassemia patients to decrease their transfusion needs. background: β-thalassemia is an inherited hemoglobin disorder caused by defective synthesis of ß-globin chains. hemoglobin (hb) f induction is a possible therapeutic approach which can partially compensate for α and non-α globin chains imbalance. objectives: we a...
transfusion of blood and its components/derivatives is a life saving medical intervention. however, this life saving procedure depends mainly on the availability of sufficient blood and its components in national health sector. therefore the overall safety of transfusion medicines including the safety of blood and its available components and the appropriate use of these components would direct...
Background Experimental studies suggest that mechanical cell washing to remove pro-inflammatory components that accumulate in the supernatant of stored donor red blood cells (RBCs) might reduce inflammation and organ injury in transfused patients. Methods Cardiac surgery patients at increased risk of large-volume RBC transfusion were eligible. Participants were randomized to receive either me...
We tested the hypothesis that allogenic adipose-derived mesenchymal stem cells (ADMSCs) alleviated brain death (BD)-induced remote organ damage and events of post heart-transplant acute rejection. To determine the impact of BD on remote organ damage, adult-male F344 rats (n=24) were categorized sham-control (SC), BD and BDMSC (allogenic ADMSC/1.2 × 106 cells/derived from F344 by intravenous tra...
BACKGROUND Blood salvage systems help to minimize intraoperative transfusion of allogenic blood. So far no data is available on the use of argatroban for anticoagulation of such systems. We conducted an ex-vivo trial to evaluate the effectiveness of three different argatroban doses as compared to heparin and to assess potential residual anticoagulant in the red cell concentrates. METHODS With...
Background: Increased costs and mortality associated with inappropriate blood transfusions have led to investigations about blood request and blood transfusion techniques. We investigated the transfusion status in patients who underwent orthopedic surgery in Poursina Hospital (Rasht, Iran) to optimizing blood usage and determine if a scheduled transfusion program for every orthopedic surgery ...
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