Fungi can be found throughout the world. They may live as saprophytes, parasites or symbionts of animals and plants in indoor as well as outdoor environment. For decades, fungi belonging to the ascomycota as well as to the basidiomycota have been known to cause a broad panel of human disorders. In contrast to pollen, fungal spores and/or mycelial cells may not only cause type I allergy, the mos...

Clinical experience has suggested the existence of an intermediate form of fungal sinusitis between the categories of non-invasive fungal sinusitis (non-IFS) and invasive fungal sinusitis (IFS). This fungal sinusitis variant demonstrates unhealthy mucosa by endoscopy with fungal invasion, but lacks angioinvasion microscopically, representing what clinically behaves as a 'pre-invasive' subtype o...

OBJECTIVES Chronic rhinosinusitis (CRS) with eosinophilic mucin is relatively rare in Korea. We categorized CRS patients with characteristic eosinophilic mucin into several groups and compared the groups based on their clinicopathological features. METHODS In total, 52 CRS patients with eosinophilic mucin were enrolled. Based on the presence or absence of an allergy (A) to a fungus or fungal ...

240 Mold Sensitization in Chronic Rhinosinusitis Patients Radoslaw Gawlik, MD, PhD, and Eugeniusz Czecior, MD, PhD. Internal Medicine, Allergy and Clin Immunology, Silesian University of Medicine, Katowice, Poland; Silesian University of Medicine, Zabrze, Poland. Background: It is estimated that about 10% of the population have IgE antibodies to common inhalant molds. Exposure to fungal allerge...

240 Mold Sensitization in Chronic Rhinosinusitis Patients Radoslaw Gawlik, MD, PhD, and Eugeniusz Czecior, MD, PhD. Internal Medicine, Allergy and Clin Immunology, Silesian University of Medicine, Katowice, Poland; Silesian University of Medicine, Zabrze, Poland. Background: It is estimated that about 10% of the population have IgE antibodies to common inhalant molds. Exposure to fungal allerge...

240 Mold Sensitization in Chronic Rhinosinusitis Patients Radoslaw Gawlik, MD, PhD, and Eugeniusz Czecior, MD, PhD. Internal Medicine, Allergy and Clin Immunology, Silesian University of Medicine, Katowice, Poland; Silesian University of Medicine, Zabrze, Poland. Background: It is estimated that about 10% of the population have IgE antibodies to common inhalant molds. Exposure to fungal allerge...

240 Mold Sensitization in Chronic Rhinosinusitis Patients Radoslaw Gawlik, MD, PhD, and Eugeniusz Czecior, MD, PhD. Internal Medicine, Allergy and Clin Immunology, Silesian University of Medicine, Katowice, Poland; Silesian University of Medicine, Zabrze, Poland. Background: It is estimated that about 10% of the population have IgE antibodies to common inhalant molds. Exposure to fungal allerge...

Objective: Rare cases of fungal balls of paranasal sinuses in children. No case has been reported in young children so far. However, allergic aspergillosis has been reported in young children. Method: A case report of 2 cases of fungal balls of paranasal sinuses in children and review of the current literature concerning fungal balls of paranasal sinuses in children are presented. Result: 2 cas...

A case report of recalcitrant allergic fungal sinusitis (AFS) refractory to systemic corticosteroids and multiple functional endoscopic sinus surgeries (FESSs) treated with anti-IgE antibody omalizumab is reported. AFS is often classified with chronic rhinosinusitis (CRS). Although similar symptoms are among the two diseases, AFS has a unique pathophysiology. Patients with AFS demonstrate type ...

Chronic rhinosinusitis (CRS) rank second at chronic inflammatory diseases in industrialized countries and are an important public health concern. Diagnosis relies on a set of arguments including clinical signs, imaging, histopathologic and mycological analyses of sinus specimens, collected during nasal endoscopy. The sensitivity of fungal cultures is reported to be poor, even when direct examin...