The evaluation of an almond collection using morphological variables and identification of self-incompatibility genotype  is useful for selecting pollinizers and for the design of crossing in almond breeding programs. In this study, important morphological traits and self-incompatibilities in 71 almond cultivars and genotypes were studied. Simple and multiplex specific PCR analyses were used in...

Background: The myotonic dystrophies (DM1, DM2) are the most common adult muscle diseases and characterized by multisystem involvement. DM1 has been described in diverse populations, whereas DM2 seems to occur primarily European Caucasians. Both caused expression of expanded microsatellite repeats. In DM1, there is a reservoir premutation alleles; however, have no reported alleles for DM...

Dear Editor Analysis of the phenylalanine hydroxylase (PAH McKusick 261600) gene in different populations has revealed more than 320 different mutations associated with phenylketonuria (PKU). One of these mutations, IVS10nt546, results in severe PAH deficiency due to defective mRNA splicing. It accounts for about 40 percent of all mutant alleles in Turkish and between 10 to 20 percent of all mu...

Abstract A proper understanding of the links between varying gene expression levels and complex trait adaptation is still lacking, despite recent advances in sequencing techniques leading to new insights on their importance some evolutionary processes. This calls for extensions continuum-of-alleles framework first introduced by Kimura (1965 Proc. Natl Acad. Sci. USA 54 731–36) that bypass class...

Major histocompatibility complex (MHC) is consisted of cluster genes known as human leukocyte antigen HLA, these are committed to process and present antigens T lymphocyte. Corona viruses, belonging a genus the corona viridae family, enveloped viruses containing single stranded RNA 27-32 kb. This study was conducted highlight some observations that may help other researcher for rapid research a...

objective: type 1 diabetes mellitus (t1d) is an autoimmune and multifactorial disorder. subsequent analysis on human leukocyte antigen ( hla) region shows that hla-drb1 and -dqb1 genes have the strongest association with t1d. in this study, for the first time, we investigated the influence of gender on the hla-drb1 and -dqb1 association with type 1 diabetes mellitus in iranian patients in order...

objective: survey of the influence of hla-drb1, -dqb1 alleles, genotypes and haplotypes on age at onset of type 1 diabetes (t1d) in an iranian population materials and methods: 105 iranian t1d patients of different ethnic group and 100 ethnically, age and sex matched individuals were selected from tehran's hospitals and hla-drb, -dqb typing was performed. according to the age at onset of t1d, ...