BACKGROUND It is a common clinical impression that fatigue is a frequent, and often debilitating, symptom in patients with chronic hepatitis C virus (HCV) infection. However, despite its obvious clinical importance, several aspects of fatigue, including its relationship with the underlying liver disease and the presence of psychologic disturbances, have not been well examined. GOALS The curre...

Chronic liver disease is a major cause of portal vein thrombosis. Further screening for other thrombotic risk factors in patients with portal vein thrombosis and chronic liver diseases is often neglected. In this paper, we report a case of portal cavernoma in a patient who was diagnosed with alcoholic liver disease and myeloproliferative neoplasm.

Liver biopsy is still useful in selected clinical situations in which it is the only tool to obtain information necessary for the diagnosis, the prognosis, and the decision for treatment. Main examples are viral hepatitis with confounding co-morbidities, non alcoholic fatty liver disease, and autoimmune liver diseases.

Background: The goal of the study was to investigate the effect of 5 weeks of high-intensity interval training (HIIT) on the levels of resistin and adiponectin and liver enzymes in Wistar rats with non-alcoholic fatty liver. Methods: To do this basic research, 24 Wistar male rats were purchased and transferred to Baqiyatallah University then, they were allocated randomly into three groups: Con...

INTRODUCTION The liver is the largest organ in the body weighing 1200-1500g. It is a key organ in regulating homeostasis within the body. It regulates several important functions including protein synthesis, storage and metabolism of fats and carbohydrates, detoxification of drugs and other toxins, metabolism of hormones and excretion of bilirubin. Liver diseases are associated with distortion ...

The high prevalence of non-alcoholic fatty liver disease (NAFLD) has made the condition an important public health issue. Two clinical entities are manifestations of NAFLD, namely, non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH). The former tends to be benign and non-progressive while the latter can progress to cirrhosis, which in rare cases gives rise to hepatocellula...