نتایج جستجو برای: albuterol

تعداد نتایج: 2227  

Journal: :Respiratory care 2015
Timothy B Op't Holt

In this issue of RESPIRATORY CARE, Johnston et al1 remind us of a route of medication delivery that is often overlooked: intratracheal. The stimulus for the project was the death of children with a severe asthma attacks who had received numerous doses of albuterol by metered-dose inhaler (MDI), yet had no relief. The purpose of this study was to compare the effectiveness of liquid bolus adminis...

Journal: :Chest 1995
M J Connolly J J Crowley N B Charan C P Nielson R E Vestal

BACKGROUND Lymphocytes of normal elderly subjects and young asthmatics display dysfunctional beta-adrenoceptors. If beta-adrenoceptor dysfunction were found in senescent airways, it might help explain the pathogenesis of late onset asthma. METHODS The bronchodilatory effects of albuterol after methacholine-provoked bronchoconstriction were compared in 17 healthy young (age 20 to 36 years) and...

Journal: :Pharmacogenetics and genomics 2009
Harriet Corvol Anthony De Giacomo Celeste Eng Max Seibold Elad Ziv Rocio Chapela Jose R Rodriguez-Santana William Rodriguez-Cintron Shannon Thyne H Geoffrey Watson Kelley Meade Michael LeNoir Pedro C Avila Shweta Choudhry Esteban González Burchard

OBJECTIVE A recent admixture mapping analysis identified interleukin 6 (IL6) and IL6 receptor (IL6R) as candidate genes for inflammatory diseases. In the airways during allergic inflammation, IL6 signaling controls the production of proinflammatory and anti-inflammatory factors. In addition, albuterol, a commonly prescribed asthma therapy, has been shown to influence IL6 gene expression. Theref...

2006
John F Freiler Rajiv Arora Thomas C Kelley Larry Hagan Patrick F Allan

STUDY OBJECTIVES The S-stereoisomer found in racemic albuterol may have associated proinflammatory properties. We tested the hypothesis that airway inflammation as assessed by exhaled nitric oxide is no different in patients with COPD when using racemic albuterol relative to levalbuterol or placebo. MEASUREMENTS Twelve mild to moderate COPD patients were assigned to five days each of nebulize...

Journal: :Chest 1996
D Hess D Fisher P Williams S Pooler R M Kacmarek

BACKGROUND Medication nebulizers are commonly used to delivery aerosolized medications to patients with respiratory disease. We evaluated output and respirable aerosol available to the patient (inhaled mass) for 17 medication nebulizers using a spontaneous breathing lung model. METHODS Three nebulizer fill volumes (3, 4, and 5 mL containing 2.5 mg of albuterol) and 3 oxygen flows (6, 8, and 1...

Journal: :Chest 2002
Rita K Cydulka E Regis McFadden Joshua H Sarver Charles L Emerman

STUDY OBJECTIVE s: The purpose of the current trial was to compare the relief of airway obstruction from treatment with a single dose of albuterol,7.5 mg (single-dose group), with that from three sequential doses of albuterol, 2.5 mg, spaced 20 min apart (multidose group). DESIGN Randomized clinical trial designed to test equivalence. SETTING Urban county hospital emergency department. PA...

2012
Pradeep H Lakshminarayana Jeremy M Kahn

BACKGROUND β2-adrenergic receptor agonists accelerate resolution of pulmonary edema in experimental and clinical studies of acute lung injury (ALI). METHODS Objective: To determine whether an aerosolized β2-agonist would improve clinical outcomes in patients with ALI. Design: Multi-center, phase III randomized, placebo-controlled clinical trial. Setting: 33 hospitals participating National He...

Journal: :P & T : a peer-reviewed journal for formulary management 2009
Nicole D Verkleeren Krista M Lipchick

The committee developed these guidelines to reflect its stance that levalbuterol should be considered a second-line therapy to albuterol and that it should be reserved for patients who experience intolerable side effects from albuterol. The guidelines did not impose restrictions on dose or frequency of levalbuterol use in patients who met these criteria; however, the pharmacists were asked to s...

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