An homogenate of rat liver which was capable of converting 2-3H-lanosta-8,24-dien-3fl-ol to 2-3H-cholest-5-en-3/3-ol failed to convert 2-3H-9, 19-cyclolanost-24-en-30-01 to 2-3Hcholest-5-en-3/3-01. However, both substrates underwent reduction at C-24,25. 2-3H-9, 19-Cyclolanost-24-en-3/?-01 was not converted to 2-3H-lanosta-8,24-dien-3P-ol. Both the presence and biosynthesis (from 2-14C-mevalona...

The vapor-phase dehydration of 1,3-butanediol (1,3-BDO) to produce 1,3-butadiene (BD) was investigated over yttrium zirconate, Y2Zr2O7, which prepared through a hydrothermal aging process. 1,3-BDO initially dehydrated three unsaturated alcohols, namely 3-buten-2-ol, 3-buten-1-ol, and 2-buten-1-ol, followed by the further BD. catalytic activity Y2Zr2O7 strongly dependent on calcination temperatu...

Terpinen-4-ol is a monoterpenoid alcohol and component of the essential oils of several aromatic plants. Similarly to terpinen-4-ol, other monoterpenoid alcohols have shown anticonvulsant activity in convulsion animal models. The present study aimed to investigate the anticonvulsant activity of terpinen-4-ol. Treatment of mice with terpinen-4-ol (200 mg/kg) caused a significant decrease in the ...

BACKGROUND AND AIM: Oral leukoplakia (OL) is a common premalignant lesion. The possible benefits of specific interventions in preventing a malignant transformation of OL are not well understood. This review assesses different invasive treatment techniques for OL and evaluate the optimal treatment possibilities.METHODS: A Medline (PubMed) search was conducted and heterogeneity between the studie...

INTRODUCTION Oral leukoplakia (OL) is the most common potentially malignant lesion of the oral cavity. AIM The purpose of the study was clinical and epidemiological analysis of patients with OL diagnosed and treated in the Department of Maxillofacial and Oral Surgery, Medical University of Gdansk, comparison of effectiveness of treatment methods, defining whether van der Waal level of OL infl...

In the present study, we show that four unusual cholesterol precursors, 5α-cholesta-8,14-dien-3β-ol, 4-methyl-5α-cholesta-8,24-dien-3β-ol (4-methylzymosterol), 4,4,14-trimethyl-5α-cholesta-8,24-dien-3β-ol (lanosterol), and 4,4-dimethyl-5α-cholesta-8,24-dien-3β-ol (4,4-dimethylzymosterol) are present in testes of the limpet Cellana grata, which is part of one of the most primitive gastropod fami...

Seven parguerane diterpenes: 15-bromo-2,7,19-triacetoxyparguer-9(11)-en-16-ol (1), 15-bromo-2,7,16,19-tetraacetoxyparguer-9(11)-ene (2), 15-bromo-2,19-diacetoxyparguer-9(11)-en-7,16-diol (3), 15-bromo-2,16,19-triacetoxyparguer-9(11)-en-7-ol (4), 15-bromo-2,16-diacetoxyparguer-9(11)-en-7-ol (5), 15-bromoparguer-9(11)-en-16-ol (6), 15-bromoparguer-7-en-16-ol (7), two polyether triterpenes: thyrsi...

Terpinen-4-ol is a terpene found in the rhizome of Plai (Zingiber montanum (Koenig) Link ex Dietr.). In this study apoptogenic activity and mechanisms of cell death induced by terpinen-4-ol were investigated in the human leukemic MOLT-4 cell line. Terpinen-4-ol exhibited cytotoxicity in MOLT-4 cells, with characteristic morphological features of apoptosis by Wright's staining. The mode of cell ...

Developing oligodendrocytes (OLs) are highly vulnerable to glutamate excitotoxicity. Although OL excitotoxicity is mainly mediated by alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors (AMPARs) and is Ca2+-dependent, the molecular basis for AMPAR-mediated Ca2+ influx in OLs remains largely unclear. Ca2+ permeability of AMPARs is inversely correlated with the abundance of the...

In this study, the structural changes of alkali lignin induced by ozonation were investigated, and effect ozone-treated its mechanism on Avicel enzymatic hydrolysis was examined. The physicochemical properties analyzed FTIR, 1H-13C HSQC NMR, GPC. It revealed that ozone pretreatment increased content carboxyl and/or aldehyde groups negative zeta potential lignin, which enhanced electrostatic rep...