Obstructive sleep apnea (OSA) is characterized by recurrent upper airway obstruction during sleep. OSA leads to high cardiovascular morbidity and mortality. The pathogenesis of OSA has been linked to a defect in neuromuscular control of the pharynx. There is no effective pharmacotherapy for OSA. The objective of this study was to determine whether upper airway patency can be improved using chem...

Beta(2)-adrenergic agonists cause a release of pulmonary surfactant into lung airways. The surfactant phospholipids maintain the patency of the conducting airways, but this function is inhibited by plasma proteins entering an inflamed airway. The physical behavior of the surfactant can be studied with a pulsating bubble surfactometer and a capillary surfactometer. Calf lung surfactant extract w...

BACKGROUND Tracheobronchial stenosis is a known complication of endobronchial tuberculosis. Despite antituberculous and steroid therapy, the development of bronchial stenosis is usually irreversible and requires airway patency to be restored by either bronchoscopic or surgical interventions. We report the use of balloon dilatation and topical mitomycin-C to successful restore airway patency. ...

Central airway stenosis caused by compression due to mediastinal cyst is rare. Direct real-time endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive method for tissue sampling of the mediastinum. Using this new therapeutic modality, the mediastinum can be punctured repeatedly and safely under local anesthesia with real-time guidance. Cystic lesion...

Objective
 Airway management in maxillofacial injuries is quite complex and involves many difficulties. The aim of this study to evaluate the knowledge level medical faculty students about airway injuries.
 Methods
 This cross-sectional was conducted on fifth sixth-grade Faculty Medicine, Afyonkarahisar Health Sciences University. After literature review, a questionnaire prepared...

Obstructive sleep apnea is caused by pharyngeal occlusion due to alterations in upper airway mechanical properties and/or disturbances in neuromuscular control. The objective of the study was to determine the relative contribution of mechanical loads and dynamic neuromuscular responses to pharyngeal collapse during sleep. Sixteen obstructive sleep apnea patients and sixteen normal subjects were...

BACKGROUND Nose is used as a corridor in endoscopic endonasal transsphenoidal approach (EETSA) for pituitary adenoma. Thus, it may affect the nasal airway patency, function and sinonasal-related quality of life. The aim of this study is to objectively and subjectively evaluate these effects. METHODS In this prospective study, 43 patients with pituitary adenoma who were candidates for EETSA fr...

Mechanisms underlying airway hyperresponsiveness are not yet fully elucidated. One of the manifestations of airway inflammation is leakage of diverse plasma proteins into the airway lumen. They include fibrinogen and thrombin. Thrombin cleaves fibrinogen to form fibrin, a major component of thrombi. Fibrin inactivates surfactant. Surfactant on the airway surface maintains airway patency by lowe...

For practicing clinicians, obstructive sleep apnea (OSA) represents an excellent illustration of how understanding adaptive physiological principles are required for optimal patient care. Clinically important OSA is estimated to affect roughly 13% of North American men, 6% of North American women, and 2% of children based on current criteria (11). The disease is characterized by repetitive coll...