Continuing the theme of a discussion of fining agents commonly used in the wine industry, we now move on to the second family of fining agents, those that do not contain proteins. Typically these agents are inorganic (with the exception of tannin) with quite specific purposes in some regards. Some are very simple to prepare and use, with physical processes constituting the bulk of the fining pr...

Obesity and overweight are major health issues. Exercise and calorie intake control are recognized as the primary mechanisms for addressing excess body weight. Naturally occurring thermogenic plant constituents offer adjunct means for assisting in weight management. The controlling mechanisms for thermogenesis offer many intervention points. Thermogenic agents can act through stimulation of the...

Most software agent lifecycles are designed in such a way that they mimic the lifecycles of humans (anthropomorphism). This position paper presents a set of operations for software agents which have no immediate biological analogies, such as splitting and merging agents. We argue through a series of scenarios the potential benefits of this approach. We present a method to implement these operat...

In this fourth paper of the series, I clarify the somewhat mysterious relation between the large class of orientation orbifolds (with twisted open-string CFT’s at ĉ = 52) and orientifolds (with untwisted open strings at c = 26), both of which have been associated to division by world-sheet orientation-reversing automorphisms. In particular – following a spectral clue in the previous paper – I s...

the majority of patients with glioblastoma multiforme (gbm) suffer dismal outcomes. adopting a broader, multi-mechanistic, multi-agent approach targeting gbm using readily available and fairly benign agents in combination with standard therapy may improve outcomes. such agents include fluoxetine, fenofibrate, cimetidine, citrulline, valacyclovir, 1,3 1-6 beta glucan, and tadalafil, among others...

Photoaging and photocarcinogenesis are primarily due to solar ultraviolet (UV) radiation, which alters DNA, cellular antioxidant balance, signal transduction pathways, immunology, and the extracellular matrix (ECM). The DNA alterations include UV radiation induced thymine-thymine dimers and loss of tumor suppressor gene p53. UV radiation reduces cellular antioxidant status by generating reactiv...

The present treatments for HIV transfection include chemical agents and gene therapies. Although many chemical drugs, peptides and genes have been developed for HIV inhibition, a variety of non-ignorable drawbacks limited the efficiency of these materials. In this review, we discuss the application of dendrimers as both therapeutic agents and non-viral vectors of chemical agents and genes for H...