To determine whether patients should participate directly in detecting adverse reactions to drugs their ability to provide written reports of symptoms experienced during treatment with amoxycillin or trimethoprim-sulphamethoxazole was investigated. When compared with telephone interviews forms on which patients reported events were reliable (the observed agreement with the same statements posed...

Spontaneous adverse drug reaction (ADR) reporting is the cornerstone of pharmacovigilance. However, underreporting is a huge problem due to lack of reporting culture amongst healthcare professionals. This cross sectional, questionnaire based study was conducted to assess the knowledge, attitudes and practices regarding adverse drug reaction reporting amongst resident (trainee) doctors. It invol...

Adverse drug reactions (ADRs) till date are still considered as one of the main problems therapy. Pharmacovigilance is monitoring safety by means spontaneous adverse-effect reporting systems, case control and cohort studies.
 This study evaluated levels awareness knowledge pharmacovigilance (i.e., ADR reporting) amongst final year students Rivers State College Health Science Technology, Po...

Immunizations against most vaccine-preventable diseases will be needed indefinitely unless the disease is eradicated. Public acceptance of immunizations may be threatened as vaccine coverage increases and disease decreases, however, due to the increase in both causally and coincidentally related vaccine adverse events. The post-marketing surveillance for such events in the USA in response to th...

Aim: To assess the attitudes and perceptions of medical practitioners towards adverse drug reaction (ADR) reporting and factors that influence the reporting of ADR. Method: A suitable self-administered survey questionnaire was designed and randomly circulated to 110 doctors in three different hospitals where local hospital based ADR reporting system exist. Results: A total of 97 filled question...

BACKGROUND Omalizumab is a monoclonal antibody, indicated for the treatment of severe allergic asthma. In Europe, there have been concerns about the cardiovascular safety of omalizumab. The objective of this study was to analyze the association between omalizumab and arterial thrombotic events in a spontaneous adverse drug reaction reporting database in the US. METHODS AND MATERIALS Reports o...