BACKGROUND Patients with pituitary adenomas usually receive "stress dose" steroids in the peri-operative peroids. Though randomized controlled trials(RCT) have not been performed to assess the necessity of steroid coverage, there are several studies that explained the changes of adrenal function during peri-operative peroids. The aim of the present study is to investigate whether it is necessar...

introduction adrenal myelolipoma is a rare benign neoplasm, which contains mature adipose tissue and variable amounts of haematopoietic elements. most lesions are small and asymptomatic, discovered incidentally during autopsy or imaging studies performed for other reasons. case presentation here we reported a series of two cases of giant myelolipomas of the adrenal gland; first one the largest ...

Adrenocortical carcinoma (ACC) is an uncommon malignancy originating from cortex of adrenal gland. The most common pitfall in diagnosis of ACC is to distinguish it from pheochromocytoma. Here we report a 62-year-old hypertensive man with presentation of dyspnea. The laboratory data showed an increase in urine cortisol and renin with a mild increase in aldosterone, but decrease in adrenocorticot...

introduction nonclassical congenital adrenal hyperplasia (cah) is characterized by sufficient cortisol and aldosterone production at the cost of androgen overproduction. hydrocortisone or dexamethasone in supraphysiological doses are current treatment; however, their downside is suppression of endogenous cortisol production resulting in corticosteroid dependency. we aimed to treat children with...

the adrenal gland of notopterus notopterus (pallas) consisted of interrenal and chromaffin cells, distributed around the main branches of posterior cardinal vein in most anterior part of the pronephric kidney. seasonal histological characteristics of the interrenal and chromaffin cells in relation to testicular activity of n. notopterus were studied by adopting different staining techniques. th...

in this study the clinical and epidemiological characteristics of congenital adrenal hyperplasia were evaluated prospectively in 47 patients admitted in imam reza hospital in mashhad during a 4 year period. 21-hydroxylase deficiency was present in 42 patients (89.3%), the simple virilizing form in 6 and the salt-losing form in 36 of them. 11b hydroxylase deficiency was present in 5 patients (10...

During the past several decades there has been increasing attention to risks of exposure endocrine disrupting chemicals, agents that mimic or block effects endogenous hormones. Previous research demonstrates may be critical periods development where factors such as prenatal stress and chemical can result in system dysregulation which manifests both immediately later life. This review describes ...

21-hydroxylase deficiency (21-OHD) caused congenital adrenal hyperplasia (CAH) is a group of autosomal recessive genetic disorders resulting from mutations in genes involved with cortisol (CO) synthesis in the adrenal glands. Testicular adrenal rest tumors (TARTs) are rarely the presenting symptoms of CAH. Here, we describe a case of simple virilizing CAH with TARTs, in a 15-year-old boy. The p...