Background and aim: Cutaneous leishmaniasis is a common disease in the world and is an endemic disease in Iran. Highly variable results of systemic treatment of cutaneous leishmaniasis with levamisole have been reported in literature so far. The purpose of this study was to evaluate the efficacy and tolerability of levamisole as an adjuvant therapy with intralesional Glucantime.<br...

Interleukin-12 (IL-12) proved to be an effective and successful adjuvant to a standard antituberculotic medication in a patient suffering from progressive clinical tuberculosis (TB). IL-12 is a potent enhancer of interferon-gamma production which is necessary for killing intracellular bacteria like mycobacteria. This patient's TB was progressive, although sensitivity to first-line antituberculo...

BACKGROUND Despite advances in the staging and surgical therapy of melanoma, patients with high-risk resected melanoma still have 5-year recurrence rates of 55% to 80% and 5-year survival rates as low as 25% to 70%. Effective adjuvant therapy is needed for this patient population. METHODS The authors review the literature regarding the use of interferon for the adjuvant therapy of resected me...

OBJECTIVE We assessed the prognostic factors and the efficacy of adjuvant therapy and reviewed randomized studies carried out on patients receiving adjuvant therapy with early endometrial carcinoma. METHODS One hundred and five patients that received primary surgical treatment for stage IB, IC and II endometrial cancer were enrolled in this study. The clinical outcomes were compared among the...

BACKGROUND On the basis of the lack of response of invasive lobular breast cancer to neoadjuvant chemotherapy, we questioned the effectiveness of adjuvant chemotherapy in relation to histology. PATIENTS AND METHODS Women with primary nonmetastatic invasive ductal or (mixed type) lobular breast cancer, aged 50-70 years, diagnosed between 1995 and 2008, were selected from the Netherlands Cancer...

Radiotherapy (RT) can be used for primary treatment, adjuvant therapy, or salvage of recurrences intracranial ependymal tumors. In recent years, there is a rising trend towards reducing the adverse effects RT by incorporation modernized techniques.

background: massive bone allograft is an option in cases of limb preservation and reconstruction after massive benign and malignant bone tumor resection. the purpose of this study was to analyze the outcome of these procedures at imam reza hospital, mashhad university of medical sciences. methods: in this study, 113 cases have been presented. eleven cases were excluded (patients has a traumatic...