OBJECTIVES The investigators undertook a systematic, comprehensive analysis of the therapeutic response and clinical outcomes of reperfusion therapy for acute ST-segment elevation myocardial infarction (STEMI) in 5,470 patients from the Assessment of the Safety and Efficacy of a New Thrombolytic Regimen (ASSENT)-3 trial. BACKGROUND Prompt effective reperfusion therapy for acute STEMI may atte...

BACKGROUND Myocardial infarction (MI) is one of the most serious challenges of contemporary cardiology. Among biochemical markers, heart-type specific fatty acid binding protein (h-FABP) has a high potential as a marker for the early diagnosis of acute MI. The h-FABP is released early to the bloodstream and may be useful for both rapid confirmation and exclusion of infarction. As opposed to pat...

Highlights of 2020 publications on acute cardiac care–acute coronary syndromes. The statements in this figure are based individual published articles and do not represent any kind recommendation. ACS, syndrome; CABG, artery bypass grafting; COVID-19, coronavirus disease 19; DAPT, dual antiplatelet therapy; FFR, fractional flow reserve; I/R, ischaemia–reperfusion; IRA, infarct-related artery; MI...

Background Infarct healing is a complex process consisting in replacement of necrotic tissue with fibrotic scar. Animal studies indicate that this process is highly anisotropic showing different patterns, which may ultimately influence left ventricular (LV) remodeling. Study aim: to investigate the influence of infarct healing on post-infarction LV remodeling in patients with acute ST-segment e...

Objectives: In the treatment of acute myocardial infarction (MI), the time delay to achieve reperfusion of the infarction-related artery has been linked to survival rates. Primary or direct angioplasty has been found to be an excellent means of achieving reperfusion in acute ST-elevation MI compared to thrombolytic therapy in randomized trials. However, no mortality benefit of primary angioplas...

Objectives: In the treatment of acute myocardial infarction (MI), the time delay to achieve reperfusion of the infarction-related artery has been linked to survival rates. Primary or direct angioplasty has been found to be an excellent means of achieving reperfusion in acute ST-elevation MI compared to thrombolytic therapy in randomized trials. However, no mortality benefit of primary angioplas...

BACKGROUND Diabetic patients with acute myocardial infarction (MI) have higher mortality than nondiabetic patients. The purpose of this study was to examine if larger infarct size explains the higher mortality in diabetic patients with acute ST-segment-elevation MI. METHODS In the CORE trial (n = 2948), subsets of patients underwent quantitative radionuclide measurement of technetium Tc 99m s...

Towards the beginning of the last century, the main role of the cardiologist was in the art of diagnosis and treatment of valvular and congenital heart disease and heart failure. This was transformed around 50 years ago with the discovery of the potential benefits of closed cardiac massage and defibrillation in the management of acute myocardial infarction (MI). Indeed, the consequent developme...

The aVR is often neglected lead. It is an unipolar lead facing the right superior surface. As all the depolarisations are going away from lead aVR, all waves are negative in aVR (P, QRS, T) in normal sinus rhythm. In dextrocardia, (True and technical) the p is upright in aVR. The lead aVR is a very important lead in localisation of Coronary Artery Disease. In the presence of anterior ST elevati...

background: the role of temperature changes, as an environmental risk factor, in the human health status has been investigated in recent studies. accordingly, the present two-year study was conducted to evaluate the incidence of myocardial infarction (mi) in warm and cold seasons in ali-ibn abi talib hospital, rafsanjan, iran. materials and methods: in this descriptive and cross-sectional study...