Introduction and objectives. The aim was to investigate the incidence and prognosis of, and predictive factors for, acute renal failure following urgent cardiac catheterization. Methods. The study involved 602 consecutive patients who underwent urgent cardiac catheterization. Acute renal failure (ARF) was defined as an increase in serum creatinine level ≥0.5 mg/dL within 72 hours following the ...

Molitoris, Bruce A., Joel M. Weinberg, Manjeri A. Venkatachalam, Richard A. Zager, Karl A. Nath, and Michael S. Goligorsky. Acute renal failure. II. Experimental models of acute renal failure: imperfect but indispensable. Am. J. Physiol. Renal Physiol. 278: F1–F12, 2000.—Acute renal failure (ARF) due to ischemic1 or toxic renal injury, a clinical syndrome traditionally referred to as acute tubu...

Chronic lymphocytic leukemia (CLL) is a malignancy characterized by clonal proliferation and accumulation of B lymphocytes. Although leukaemic infiltration of the kidney is well recognized in CLL, acute renal failure (ARF) due to leukaemic infiltration is extremely rare. Here we present a case of ARF as the initial manifestation of CLL. The diagnosis was made by a kidney biopsy. Treatment with ...

Generation of reactive oxygen species significantly contributes to the pathogenesis of acute renal failure (ARF) induced by myoglobin release. Ginsenosides (GS), the principal active ingredients of ginseng, is considered as an extremely good antioxidative composition of Chinese traditional and herbal drugs. The purpose of the present study was to investigate the protective effect of ginsenoside...

BACKGROUND The renal effects of cyclooxygenase-2 (COX-2) inhibitors have been incompletely elucidated, and acute renal failure (ARF) due to COX-2 inhibitors has been reported. METHODS In order to determine the causes of ARF and hyperkalaemia in five patients during COX-2 inhibitor therapy, we carefully analysed case studies of consecutive in-patients or out-patients referred to our Renal Divi...

Bonventre, J. V., M. Brezis, N. Siegel, S. Rosen, D. Portilla, and M. Venkatachalam. Acute renal failure. I. Relative importance of proximal vs. distal tubular injury. In: Acute renal failure forum, edited by W. Lieberthal and S. K. Nigam. Am. J. Physiol. 275 (Renal Physiol. 44): F623–F632, 1998.—For more than 15 years, there has been an ongoing debate regarding the nephron segment(s) most seve...

Acute renal failure (ARF), induced by either toxins or ischemia, is associated with significant morbidity. The pathogenesis of ARF is complex and is characterized by renal vasoconstriction and oxidative stress in association with tubular and microvascular injury and interstitial inflammation. In many situations, ARF is associated with a rise in serum uric acid as a result of both increased gene...

Bonventre, J. V., M. Brezis, N. Siegel, S. Rosen, D. Portilla, and M. Venkatachalam. Acute renal failure. I. Relative importance of proximal vs. distal tubular injury. In: Acute renal failure forum, edited by W. Lieberthal and S. K. Nigam. Am. J. Physiol. 275 (Renal Physiol. 44): F623–F632, 1998.—For more than 15 years, there has been an ongoing debate regarding the nephron segment(s) most seve...