نتایج جستجو برای: acute oral toxicology

تعداد نتایج: 741419  

Journal: :International Journal of Health Sciences (IJHS) 2022

The purpose of this study is to evaluate the acute oral toxicity Turmeric based herbal product in sprague dawley rats. Acute refers those adverse effects occurring following administration a single dose substance, or multiple doses given within 24 hours. LD50 value, defined as statistically derived that, when administered an test, expected cause death 50% treated animals period, currently basis...

Journal: :iranian journal of basic medical sciences 0
selmi slimen laboratory of animal physiology, department of biology, faculty of sciences, university tunis el manar, tunis, tunisia el fazaa saloua laboratory of animal physiology, department of biology, faculty of sciences, university tunis el manar, tunis, tunisia gharbi najoua laboratory of animal physiology, department of biology, faculty of sciences, university tunis el manar, tunis, tunisia

objective(s):the present study was undertaken to determine the effects of acute exposure to malathion on oxidative stress and cytotoxic potential of anticholinesterase insecticide, malathion in reproductive toxicology of adolescent male mice. materials and methods: thirty two adolescent male mice at pubertal age were treated with 500 mg/kg body weight (bw) of malathion for three days. after exp...

Journal: :Chemical research in toxicology 2009
Desmond I Bannon James F Dillman Michael A Hable Christopher S Phillips Edward J Perkins

RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) is a synthetic, high-impact, relatively stable explosive that has been in use since WWII. Exposure to RDX can occur in occupational settings (e.g., during manufacture) or through the inadvertent ingestion of contaminated environmental media such as groundwater. The toxicology of RDX is dominated by acute clonic-tonic seizures at high doses, which re...

Journal: :jundishapur journal of natural pharmaceutical products 0
lana tamaddon department of pharmaceutics, isfahan pharmaceutical sciences research center, school of pharmacy and pharmaceutical sciences,isfahan university of medical sciences, isfahan, ir iran abolfazl mostafavi department of pharmaceutics, isfahan pharmaceutical sciences research center, school of pharmacy and pharmaceutical sciences,isfahan university of medical sciences, isfahan, ir iran; department of pharmaceutics, isfahan pharmaceutical sciences research center, school of pharmacy and pharmaceutical sciences, isfahan university of medical sciences, isfahan, ir iran. tel: +98-3116688064 mohammad riazi-esfahani eye research center, farabi eye hospital, tehran university of medical sciences, tehran, ir iran reza karkhane eye research center, farabi eye hospital, tehran university of medical sciences, tehran, ir iran sara aghazadeh eye research center, farabi eye hospital, tehran university of medical sciences, tehran, ir iran morteza rafiee-tehrani department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, ir iran

background the treatment of posterior eye diseases is always challenging mainly due to inaccessibility of the region. many drugs are currently delivered by repeated intraocular injections. objectives the purpose of this study was to investigate the potential applications of natural triglycerides as alternative carriers to synthetic polymers in terms of drug release profile and also biocompatibi...

2012
Advait Nagle Tao Wu Kelli Kuhen Kerstin Gagaring Rachel Borboa Caroline Francek Zhong Chen David Plouffe Xuena Lin Christopher Caldwell Jared Ek Suzanne Skolnik Fenghua Liu Jianling Wang Jonathan Chang Chun Li Bo Liu Thomas Hollenbeck Tove Tuntland John Isbell Tiffany Chuan Philip B. Alper Christoph Fischli Reto Brun Suresh B. Lakshminarayana Matthias Rottmann Thierry T. Diagana Elizabeth A. Winzeler Richard Glynne David C. Tully Arnab K. Chatterjee

On the basis of the initial success of optimization of a novel series of imidazolopiperazines, a second generation of compounds involving changes in the core piperazine ring was synthesized to improve antimalarial properties. These changes were carried out to further improve the potency and metabolic stability of the compounds by leveraging the outcome of a set of in vitro metabolic identificat...

Journal: : 2021

This article analyzes modern scientific sources on the problems of detection toxic substances in human body, considers existing methods toxicological examination used practical forensic medicine to establish and differentiate acute intoxications with various chemical compounds. Despite presence a large number analysis, diagnosis poisoning is often complicated due lack data circumstances event, ...

Journal: :Middle East journal of digestive diseases 2016
Hassan Vossoughinia Ali Pourakbar Samaneh Esfandiari Masoud Sharifianrazavi

A 19-year-old woman was referred to the Emergency Surgery Department with severe abdominal pain, icterus, and anemia. The patient's clinical and paraclinical findings in addition to her occupational and social history, convinced us to assay blood lead level (BLL), which was 41/5 μg/dL. Therefore toxicology consult was performed to treat lead toxicity. Recheck of the BLL showed the level as 53/7...

Journal: :Metal-Based Drugs 2000
Walter Goessler

Goals and Scope The ICEBAMO meetings aim to facilitate interdisciplinary discussion on environmental and biological aspects of main-group organometals. have brought together researchers from the fields of toxicology, environmental sciences, analytical chemistry, biochemistry, and synthetic organometallic chemistry. ICEBAMO 2001 at the castle of Schieileiten, which is located about 50 km east of...

2018

1 THE TOXIC EFFECTS OF THE MERCURY IN DENTAL AMALGAM FILLINGS ON THE ENVIRONMENT AND HUMAN HEALTH A FACT SHEET PREPARED BY The International Academy of Oral Medicine and Toxicology www.iaomt.org “For medical reasons, amalgam should be eliminated in dental care as soon as possible. As a result, one of our largest sources of mercury in the environment can be eliminated.’’ 1 --Dr. Maths Berlin, th...

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