abstract the usage of heroin is associated with a variety of neurologic disorders, including acute transverse myelitis. in this study we present a 19 year old man who was suffered from insufflated heroin after several months of abstinence, and admitted to hospital emergency department, unconscious. he responded to fluid therapy and naloxone, but could not move his legs on examination. he had fl...

Alexander L. Greninger, M.D., Ph.D., Samia N. Naccache, Ph.D., Kevin 4! Messacar, M.D., Anna Clayton, B.S., M.P.H., Guixia Yu, B.S., Sneha Somasekar, 5! B.S., Scot Federman, B.A., Doug Stryke, B.S., Christopher Anderson, B.S, 6! Shigeo Yagi, Ph.D., Sharon Messenger, Ph.D. , Debra Wadford, Ph.D. , Dongxiang 7! Xia, M.D., Ph.D., James P. Watt, M.D., M.P.H. , Keith Van Haren, M.D., Samuel R. 8! Do...

  Abstract   The usage of heroin is associated with a variety of neurologic disorders, including   acute transverse myelitis. In this study we present a 19 year old man who was suffered   from insufflated heroin after several months of abstinence, and admitted to hospital   emergency department, unconscious. He responded to fluid therapy and Naloxone,   but could not move his legs on examinatio...

Encephalitis is a devastating illness that commonly causes neurologic disability and has a case fatality rate >5% in the United States. An etiologic agent is identified in <50% of cases, making diagnosis challenging. The Centers for Disease Control and Prevention Emerging Infections Program (EIP) Encephalitis Project established syndromic surveillance for encephalitis in New York, California, a...

Spinal anesthesia is widely used during surgical procedures. It is generally safe and the frequency of severe, permanent neurological complications associated with it has been reported to be extremely low. We report a patient, who developed paraplegia following spinal anesthesia. A 29-year-old male was referred with acute, flaccid, sensory motor paraplegia, with bladder and bowel involvement. H...

BACKGROUND Acute flaccid paralysis (AFP) can be caused by a number of conditions. A common preventable cause is poliomyelitis which is still being reported in Pakistan, Guillain Barre Syndrome (GBS), also known as Acute Inflammatory Demyelinating Polyneuropathy, is another common cause of acute flaccid paralysis. It is important to recognize GBS in childhood as parents consider all acute flacci...

Acute transverse myelitis is a clinical syndrome affecting the spinal cord, which is characterized by acute onset of motor, sensory, and autonomic dysfunction. Approximately 20% of cases of acute transverse myelitis occur in children. This review summarizes the current published literature on acute transverse myelitis, including epidemiology, diagnostic criteria, pathogenesis, clinical presenta...

More or less severe asthma attacks can damage the CNS and peripheral system in adults and children, both directly causing hypoxia and indirectly with the production of autoimmune antibodies. The pathogenic mechanism is still unknown; cytokines, TNFs, interleukins, free radicals and nitric oxide are often involved as causative factors for the disorders [1,2]. In this review we focus our attentio...