Acute disseminated encephalomyelitis (ADEM) also known as post infectious encephalomyelitis is a demyelinating disease of the central nervous system (CNS) that typically presents as a monophasic disorder associated with multifocal neurological symptoms and disability. It may follow vaccination in children or infection. Viral infection like measles, rubella, influenza, Epstein bar, HIV, herpes, ...

OBJECTIVE To determine the frequency, etiology (viral infection or vaccination), presenting signs and symptoms, response to therapy, complication and course of acute disseminated encephalomyelitis (ADEM) in our hospitals. METHODS A 2-year retrospective, descriptive, chart review of children with final diagnosis of ADEM in 2 hospitals (Hazrat Rasool and Mofid in Tehran, Iran during 2000-2002) ...

PURPOSE To review the frequency, distribution, and extent of deep gray matter disease in children with acute disseminated encephalomyelitis. METHODS The MR examinations of 10 patients, who were discharged with the clinical diagnosis of acute disseminated encephalomyelitis between 1986 and 1992, were retrospectively reviewed. Locations of abnormal signal in the cerebral and cerebellar cortices...

BACKGROUND AND PURPOSE White matter lesions on MR images obtained from patients with acute disseminated encephalomyelitis (ADEM) have been reported to appear shortly after symptom onset, and their resolution has been claimed to parallel recovery. To elucidate the temporal evolution of these lesions and to associate the changes on MR images to the patients' clinical condition, we performed seria...

1434 The MG Composite: A valid and reliable outcome measure for myasthenia gravis T.M. Burns, M. Conaway, and D.B. Sanders, on behalf of the MG Composite and MG-QOL15 Study Group 1441 Mexiletine is an effective antimyotonia treatment in myotonic dystrophy type 1 E.L. Logigian,W.B.Martens,R.T.Moxley IV, M.P.McDermott,N.Dilek,A.W.Wiegner,A.T. Pearson, C.A.Barbieri, C.L. Annis,C.A. Thornton, andR....

症 例 症例1:38歳,男 性.主 訴:意 識 障害.既 往 歴:10歳 気管 支喘息.家 族歴:父 が糖尿病 と大 腸癌.母 が糖 尿病 と胆嚢癌.現 病歴:2002年12 月末 より発熱,頭 痛があ り,翌 年1月 初旬 に尿 閉 と意識障害が出現 し当院を受診 し入院 となっ た.入 院時現症:体 温38.1度以 外は一般 身体所 見 に異常は なかった.意 識障害(JCS3)と 項部 硬直,両 下肢の腱 反射低下 を認めた.病 的反射 は陰性 であった.5日 後の歩行 は失調性で,両 下 肢の ジンジ ンした しびれ を訴え,Th7以 下の表 在感覚低 下 と尿 閉を呈 した.入 院時検査:WBC 6,400/μl,CRP0.9mg/dl.髄 液はキサ ン トクロ ミーを呈 し,細 胞数307/mm3(多 核球67,リ ン パ 球240),蛋 白204mg/dl,糖47mg/...

Investigators from Ruth Children's Hospital, Haifa, and Schneider Medical Center, Petah Tikuah, Israel, evaluated the long-term motor and neurocognitive outcome of 43 children hospitalized during 2002-2012 with acute disseminated encephalomyelitis (ADEM), and identified prognostic risk factors.

Rapid production in the monkey of a pathological condition resembling acute disseminated encephalomyelitis, marked by demyelination, can be achieved by the use of adjuvants added to rabbit brain emulsions.

We report a seven year old male with measles associated acute disseminated encephalomyelitis (ADEM) despite having received measles vaccination in infancy. The diagnosis was based on serum antimeasles antibodies and MRI brain. The patient was managed with high dose corticosteroids along with supportive measures. There was a complete neurologically and physica recovery.