This article compares two hypotheses regarding the mechanisms responsible for aging in humans and other mammals. In the passive mechanism, aging is the result of inadequacies in maintenance and repair functions that act to prevent or repair damage from fundamental deteriorative processes. In the active mechanism, a life span management system purposely limits life span by deactivating maintenan...

In recent years, the global trend of population aging and its inherent features have changed research agenda for studying older age groups. The paper is devoted to definition main subject areas that are in focus active delayed Russia abroad. For scientometric analysis, databases Scopus eLibrary (RSCI) were used. study used method mapping using VOSviewer program. following terms chosen as search...

Active aging technologies are increasingly designed to support an active lifestyle. However, the way in which they can raise different barriers acceptance of and use by older adults. Their designers adopt a negative stereotype aging. Thorough understanding user requirements is central this problem. This paper investigates for that encourage lifestyle provide people with means self-manage their ...

OBJECTIVES The aim of this study was to evaluate left atrial volume and its changes with the phases (active and passive) of atrial filling, and to examine the effect of normal aging on these parameters and pulmonary vein (PV) flow patterns. BACKGROUND Atrial volume change with normal aging has not been adequately described. Pulmonary vein flow patterns have not been volumetrically evaluated i...

Healthy life span is rapidly increasing and human aging seems to be postponed. As recently exclaimed in Nature, these findings are so perplexing that they can be dubbed the 'longevity riddle'. To explain current increase in longevity, I discuss that certain genetic variants such as hyper-active mTOR (mTarget of Rapamycin) may increase survival early in life at the expense of accelerated aging. ...