The present study aimed to investigate the role of adenylyl cyclase activator in preventing diabetic nephropathy via antioxidant activity in rats. Biochemical parameters were performed to confirm Streptozotocin induced nephropathy in rats. Male Wistar rats were used in the present study to reduce the effect of estrogen. Rats were subjected to high fat diet (HFD) for two weeks followed by low do...

Endoglycoceramidase (EGCase) cleaves the linkage between oligosaccharides and ceramides of various glycosphingolipids (Ito, M., and Yamagata, T. (1986) J. Biol. Chem. 261, 14278-14282). Recently, by extensive purification, it was separated from cell-lytic factor (hemolysin) and found to consist of three molecular species each with its own specificity (EGCases I, 11, and 111) (Ito, M., and Yamag...

Abstract This research aimed to present the improvement of cementitious material in high-volume fly ash using only one alkali activator. Fly was used as a partial replacement for Portland cement type I, varying from 0 60% by weight binder. Concentrations NaOH 0.00 1.25 molar were Paste properties and mortar compressive strength at ages 3, 7, 14, 28, 60, 90 days water curing investigated. The re...

Abstract One of the critical factors affecting performance alkali-activated slag (AAS) is nature and dose alkali activator. The activator type can play a significant role during transition from pastes to mortars or concretes. Therefore, three basic sodium activators (water glass, carbonate, hydroxide) same molarity 4M Na + were used prepare AAS-based with different volume fractions siliceous sa...

Background: To analyze the correlations between plasma coagulation factor VII (FVII), plasminogen activator inhibitor-1 (PAI-1), uric acid, and insulin resistance (IR) diabetic macroangiopathy (DMAP) in elderly patients with type 2 diabetes mellitus (T2DM).

Bradykinin stimulates tissue plasminogen activator release from human endothelium through a flow-independent, B2 receptor-dependent mechanism. The present study tests the hypothesis that smoking impairs bradykinin-stimulated tissue plasminogen activator release. Graded doses of nitroprusside (1.6 to 6.4 microg/min), methacholine (3.2 to 12.8 microg/min), and bradykinin (100 to 400 ng/min) were ...

AIM The aims of this study were to evaluate the dental changes brought about by activator and activator headgear combination (ACHG) and to determine whether we can achieve control over the lower incisor proclination which is a side effect of using functional appliances; or not, while treating cases of skeletal class II malocclusions. METHODS Lateral cephalograms of 45 skeletal class II divisi...

The calpains (E.C. 3.4.22.17) and calpastatin constitute an ubiquitous, intracellular, Ca2+dependent protease/inhibitor system. This system has been implicated as a principal regulator of myofibrillar protein degradation in both ante-mortem and postmortem muscle. Although proteolytic activity of the calpains is primarily controlled through interaction of calpain and calpastatin, evidence for an...

We studied the incidence of cerebral hemorrhage in an animal model of embolic stroke to determine the safety of aspirin, heparin, and tissue plasminogen activator therapies. We occluded the middle cerebral arteries of rabbits with labeled blood clots and administered either tissue plasminogen activator, heparin, aspirin, tissue plasminogen activator plus aspirin, tissue plasminogen activator pl...