BACKGROUND Clinical diagnosis of actinic keratosis is known to have intra- and inter-observer variability, and there is currently no non-invasive and objective measure to diagnose these lesions. OBJECTIVE The aim of this pilot study was to determine if automatically detecting and circumscribing actinic keratoses in clinical photographs is feasible. METHODS Photographs of the face and dorsal...

Chronic exposure to environmental ultraviolet radiation (UVR) plays a key role both in photocarcinogenesis and induction of accelerated skin ageing. Sailors commonly experience a significant number of cutaneous problems, related to the exposure to environmental factors due to their working conditions. Among these factors, sun exposure is able to determine both acute and chronic skin damage, mos...

Complete patient clearance is often required by regulatory agencies for the approval of treatments for actinic keratosis (AK). However, an increasing number of clinicians have challenged the use of this measure in clinical practice and its interpretation. It has been argued that complete patient clearance often underestimates the clinical benefit of a drug and is influenced by a number of key c...

Background: Seborrheic keratoses are benign intraepidermal neoplasms arising from epidermal keratinocytes. Age and UV exposure have a role in the course of disease. keratosis consists several types cells, transformation into various epithelial tumors originating same cell type can occur. Therefore, basal carcinoma may arise basaloid which is most commonly reported malignant neoplasm seborrheic ...

Abstract Convolutional Neural Network (CNN) is a branch of deep learning which has been one popular methods in different applications, especially medical field. In this study, an optimized CNN model built using the random search optimization to classify seven types skin cancer, namely, basal cell carcinoma, melanoma, dermatofibroma, vascular lesion, melanocytic nevus, actinic keratosis and beni...

In consideration of the development treatment options for squamous cell carcinoma (SCC), Japanese Skin Cancer Society issued first guidelines SCC in 2007 and revised them 2015. Here, we report English version 2020 edition guidelines. The half this article is an overview including actinic keratosis Bowen’s disease, second discusses three clinical questions: (i) keratosis; (ii) determination rese...

Topical treatment for actinic keratosis with 5% fluorouracil has a recurrence rate of 54% in 12 months of follow-up. This study analyzed thirteen actinic keratoses on the upper limbs through confocal microscopy, at the time of clinical diagnosis and after 4 weeks of treatment with fluorouracil. After the treatment was established and evidence of clinical cure was achieved, in two of the nine ac...