Acridine is a heterocyclic nucleus. It plays an important role in various medicines. A number of therapeutic agents are based on acridine nucleus such as quinacrine (antimalarial), acriflavine and proflavine (antiseptics), ethacridine (abortifacient), amsacrine and nitracine (anticancer), and tacrine. Acridine is obtained from high boiling fraction of coal tar. It is also obtained in nature fro...

A fully kinetoplastic strain of an antigenic variant of Trypanosoma equiperdum has been made dyskinetoplastic by successive treatments of infected rats with ethidium bromide or acriflavine. After seven passages in the absence of the dye, the loss of kinetoplast DNA (kDNA) is stable and complete as shown by analytical ultracentrifugation, CsCl-dye gradients, and the reassociation kinetics of in ...

In the search for functional organic biomaterials, leather constituted by collagen fibers was coated with a conducting polymer, polypyrrole. The coating carried out during oxidation of pyrrole in an aqueous solution poly(N-vinylpyrrolidone) presence five dyes: crystal violet, neutral red, methyl orange, acriflavine, and methylene blue. This technique ensures uniform polypyrrole incorporation dy...