There is no single malady which causes supplementary psychic disturbance and more general insecurity and feeling of inferiority than acne vulgaris with post inflammatory acne pigmentation marks does. It is strongly associated with depression and anxiety. In addition to individuals with little objective evidence acne with post inflammatory acne hyperpigmentation marks may endure severe subjectiv...

OBJECTIVE To determine if there are differences in the activity of 17beta-hydroxysteroid dehydrogenase and 5alpha-reductase (responsible for the production of testosterone and dihydrotestosterone, respectively) in sebaceous glands obtained from men and women with and without acne. DESIGN Single-center examination of androgen levels and sebaceous gland enzyme activity in a cohort of volunteers...

BACKGROUND In westernized societies, acne vulgaris is a nearly universal skin disease afflicting 79% to 95% of the adolescent population. In men and women older than 25 years, 40% to 54% have some degree of facial acne, and clinical facial acne persists into middle age in 12% of women and 3% of men. Epidemiological evidence suggests that acne incidence rates are considerably lower in nonwestern...

INTRODUCTION Ceramide-containing moisturizers may offer benefits as an adjunct to acne treatment. METHODS An expert panel of 11 Canadian dermatologists, including an international clinical scientist, used the following modified Delphi process: 1) A systematic literature review for acne treatment, dry skin, irritation, depletion of ceramides in acne, and benefits of moisturizers and ceramide-c...

Acne is a common complaint in the primary care clinics. It has not only physical implications but also psychological. This article discusses the epidemiology, pathophysiology, and criteria for making the diagnosis. It also discusses endocrine disorders that may be the cause of acne. Treatment and management are discussed by subtype. Acne mechanica or sports-related acne is also discussed.

HS: hidradenitis suppurativa IL: interleukin LCV: leukocytoclastic vasculitis PAPA: pyogenic arthritis, pyoderma gangrenosum, and acne PAPASH: pyogenic arthritis, pyoderma gangrenosum, acne, and hidradenitis suppurativa PASH: pyoderma gangrenosum, acne, and hidradenitis suppurativa PG: pyoderma gangrenosum PsAPASH: psoriatic arthritis, pyoderma gangrenosum, acne, and hidradenitis INTRODUCTION A...

BACKGROUND The incidence of preadolescent acne among women is increasing. Acne deteriorates the quality of life; conventional treatment options are limited and have not been effective against acne, particularly acne associated with menstruation. Despite evidence that acne associated with menstruation abnormalities naturally improves when menstruation recovers to normal, there have only been few...

INTRODUCTION The negative impact of acne on aspects of health-related quality of life (HRQL) has been demonstrated in many quantitative studies; however, there has been relatively little qualitative research exploring the impact of acne and the use of topical treatment. The study aimed to explore the impact of moderate-severe acne on HRQL in adolescents and adults with inflammatory and non-infl...