1. Levin AS, Barone AA, Penço J, et al. Intravenous colistin as therapy for nosocomial infections caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumanii. Clin Infect Dis 1999; 28:1008–11. 2. Stein A, Bataille JF, Drancourt M, et al. Ambulatory treatment of multidrug-resistant Staphylococcus–infected orthopedic implants with high-dose oral co-trimoxazole (trimethoprim-su...

Rubus parvifolius L. (Rp) is a medicinal herb that possesses antibacterial activity. In this study, we extracted the volatile oil from the leaves of Rp to assess its antibacterial activity and analyze its chemical composition. A uniform distribution design was used to optimize the extraction procedure, which yielded 0.36% (w/w) of light yellowish oil from the water extract of Rp leaves. We foun...

Results In the study period, 4 patients had tracheal aspirate (TA) positive for MDR A.baumanii (all on mechanical ventilation), one patient had positive catheter tip and blood cultures. The attack rate was 12,8% and the ventilator associated pneumonia rate rose from 20,30 to 34,96 per 1000 ventilator days. The first three cases occurred from September 13 to 20 all of them in TA. Contact precaut...

Problems with antibiotic resistant bacteria are increasing in the hospital and particularly in the intensive care unit. Methicillin-resistant Staphylococcus aureus, Acinetobacter baumanii and extended spectrum beta-lactamase producing gram-negative bacilli constitute a therapeutic and infection control challenge. Early enteral feeding improves survival in patients in the intensive care unit. Pr...

Background: Increasing antimicrobial resistance of microbes is one the leading challenges faced by medical community and human health. This study focused on a local scorpion species (Buthus sindicus) Pakistan known for its potent antibiotic properties against Carbapenem-resistant Acinetobacter baumannii Pseudomonas aeruginosa. Methodology: Venom extracted from Buthus sindicus tested A. P. aerug...

Methanol, acetone and ethyl acetate extracts obtained from Verbascum pinnatifidum Vahl. V. antinori Boiss. et Heldr were investigated for their bioactive composition, antimicrobial antibiofilm activity. Antimicrobial activity was determined with Escherichia coli NRRL B-3704, Pseudomonas aeruginosa ATCC 27853, Proteus vulgaris 13315, Acinetobacter baumanii 19606), Bacillus subtilis 6633, Staphyl...

Acinetobacter spp. are gram-negative aerobic coccobacilli that are ubiquitous in nature, persistent in the hospital environment, and cause a variety of opportunistic nosocomial infections (Bergogne-Berezin et al, 1996). They cause various types of human infections. Of the currently known 31 Acinetobacter species, Acinetobacter baumannii is the most prevalent in clinical specimens. A number of s...

Methods Observational analysis using ENVIN-HELICS database of all the infected and/or colonized patients in our ICU between January and May 2014 and to describe the multi-disciplinary measures performed for it ́s control: hygiene measures (strict hand hygiene, patients daily wash with special chlorhexidine gel, strict contact isolation), clustering measures (grouping all positive patients in ICU...