Abstract Repulsive electrostatic forces between prion‐like proteins are a barrier against aggregation. In neuropharmacology, however, prion's net charge ( Z ) is not targeted parameter. Compounds that selectively boost prion remain unreported. Here, we synthesized compounds amplified the negative of misfolded superoxide dismutase‐1 (SOD1) by acetylating lysine‐NH 3 + in amyloid‐SOD1, without na...

Sugar recognition specificities of class III (OsChib1a) and class I (OsChia1cDeltaChBD) chitinases from rice, Oryza sativa L., were investigated by analyzing (1)H- and (13)C-nuclear magnetic resonance spectra of the enzymatic products from partially N-acetylated chitosans. The reducing end residue of the enzymatic products obtained by the class III enzyme was found to be exclusively acetylated,...

acetylation is a chemical modification of wood to enhance its properties. ir-spectroscopy is a useful technique for proofing chemical bondings in wood and the at-tenuated total reflection (atr) infrared spectroscopy technique was applied as an eas-ier technique over other ir-spectroscopies. in this research, different degrees of acetyla-tion, weight percentage gains (wpgs) in beech and pine min...

BACKGROUND Acetylation of the xylan backbone restricts the hydrolysis of plant poly- and oligosaccharides by hemicellulolytic enzyme preparations to constituent monosaccharides. The positional preferences and deacetylation efficiencies of acetyl esterases from seven different carbohydrate esterase (CE) families towards different acetylated xylopyranosyl units (Xylp) - as present in 4-O-methyl-g...

N(α)-terminal acetylation of peptides plays an important biological role but is rarely observed in prokaryotes. N(α)-terminal acetylated thymosin α1 (Tα1), a 28-amino-acid peptide, is an immune modifier that has been used in the clinic to treat hepatitis B and C virus (HBV/HCV) infections. We previously documented N(α)-terminal acetylation of recombinant prothymosin α (ProTα) in E. coli. Here w...