A major difference between the prostate and other accessory reproductive glands is the susceptibility of the prostate to hyperplasia in again men. Indeed, benign hyperplasia of the prostate (BPH) affects most males over 60 years of age and causes enlargement of the inner gland. When the urethra becomes constricted, treatment is required to relieve the kidney and circulation system of the damagi...

Background: Hypothalamus-derived kisspeptins are critical regulators of reproduction in nearly all mammalian species including the humans. These small peptides mediate their actions through the GnRH loop system. How kisspeptins regulate gonadal maturation in sexually immature male mammals remains elusive. To address this, kisspeptin was administered as subchronic (12 days) twice daily i. p. dos...